Identification and characterization of novel peptides in snake venom that pharmacologically modulate the human P2X4 receptor (360G-Wellcome-211430_Z_18_Z)

£0

P2X receptors are ligand-gated ion channels activated by extracellular ATP. The human genome encodes seven receptors (P2X1-7) of which the P2X4 receptor has emerged as a promising drug target for the treatment of neuropathic pain and hypertension. However, progress in this area has been severely hampered by a paucity of selective small molecule modulators of P2X4. This project will seek to identify and characterise novel snake venom peptides that can pharmacologically manipulate the activity of the human P2X4 receptor.

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Grant Details

Amount Awarded 0
Applicant Surname Campbell
Approval Committee Internal Decision Panel
Award Date 2018-05-31T00:00:00+00:00
Financial Year 2017/18
Grant Programme: Title Vacation Scholarships
Internal ID 211430/Z/18/Z
Lead Applicant Mr Sam Campbell
Partnership Value 0
Planned Dates: End Date 2018-09-01T00:00:00+00:00
Planned Dates: Start Date 2018-07-02T00:00:00+00:00
Recipient Org: Country United Kingdom
Region East of England