Chemistry in Cells – New Technologies to Probe Complex Biology and Medicine. (360G-Wellcome-218514_Z_19_Z)

This Programme will provide unique training for a new generation of scientists focusing on the quantification of biologically-important molecular interactions in physiologically-relevant settings. It is currently impossible to accurately and directly quantify interactions of molecules, and their consequences, in the complex physiological settings relevant to diagnosis and treatment of disease. To address this unmet need, we will harness physical science-based approaches to develop technologies that will underpin research across the spectrum of cell biology and biomedical science Scientific goals: Collaborative research outputs (papers, patents) using innovative approaches to provide new insights into biomedicine. Adoption of our technologies by the broad biomedical research community to study fundamental biology/diseases including Alzheimer’s, schizophrenia and cancer. We have developed an innovative framework for our training programme, promoting a diverse and positive research culture change that we aim to propagate across Oxford and the UK. Culture-change goals: Promotion of a positive research culture in Oxford demonstrated by uptake of our practices across the University. Communication of our strategies via lectures on graduate education and publications in educational journals. These ambitious goals provide an exceptional basis for a multidisciplinary programme that trains scientist equipped as problem solvers for a diverse range of 21stcentury workplaces.