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40 years of Family Research. 28 Mar 2006

Title of meeting: 40 years of Family Research Martin Richards has been an eminent researcher in many areas of family research and it is probably not an exaggeration to describe him as one of the pioneers in the field of psychological and social aspects of 'new' human genetics. He has raised important questions, developed research and contributed greatly in areas such as genetic screening, consent and bioethics. He has given generously of his time to serve on many committees in associated areas. The occasion of his retirement seems an appropriate time to reflect on his contributions and the way his work can be taken forward.

Amount: £750
Funder: The Wellcome Trust
Recipient: University of Cambridge

Conference entitled 'In the age of al-Farabi: Arabic thought in the 4th/10th Century'. 22 Nov 2005

In the Age of al-Farabi: Arabic Thought in the 4th/10th Century The proposed conference is one of a series of events focusing on philosophy in the Islamic world (we use the phrase "Arabic Philosophy" since some of the philosophers to be discussed were in fact Christian and Jewish). Previous events in this series have had a broader focus, dealing with a range of topics throughout the history of Arabic thought. But in order to produce as coherent an event as possible, this conference will focus more tightly on the most philosophically vibrant and historically important century in Arabic thought: the 10th century (the 4 century of the Islamic calendar). The purpose of this conference is to look at al-Farabi and other philosophers within the complex intellectual context of the 10th century itself. This involves two basic tasks: First, we will take account of the full range of philosophical schools and traditions of this time period. The most famous of these is the Aristotelian school in Baghdad; the Muslim al-Farabi was a member of this school, but most of these Aristotelians were in fact Christians. Several papers will be devoted to this school: those by Black, Eggert, Ferrari, Giannakis, Rashed, Reisman and Urvoy. A rival development were the more Platonist philosophers who lived and worked further east in the Islamic empire. The papers by Adamson, Biesterfeldt and Wakelnig will discuss these thinkers. Meanwhile, there are philosophical movements that are harder to classify - one of the goals of the conference will be to explore how other thinkers relate to the major trends of the period. Thus Fenton will speak on Jewish thinkers of the time, and there will be papers on the enigmatic "Brethren of Purity" and other authors with Shiite Ismaili leanings. Second, we will consider intellectual developments that were related to philosophy, without however involving thinkers who would necessarily have described themselves as "philosophers". There are three such developments to be explored: science, and especially medicine; the trend of refined literary authors who show knowledge of and interest in philosophical texts; and perhaps most importantly indigenous Islamic theology, or "kalam".

Amount: £516
Funder: The Wellcome Trust
Recipient: King's College London

'The importance of medical history: Transnational and cross-cultural perspectives on a multi-faceted discipline' conference to be held in Mumbai, India from 15th to 17th November 2007. 17 Oct 2007

The importance of medical history: Trans-national and cross-cultural perspectives on a multi-faceted discipline The proposed meeting will be the first of its type in the South Asian sub-continent - dealing with the important questions of historical method and historiography, from trans-national and cross-disciplinary perspectives; it will allow the audience access to a plethora of perspectives on how to study HOM. The projected audience will be university and college teaching, research and administrative staff of all grades, we well as undergraduate and post-graduate students, doctors, print and TV journalists, and independent researchers. A number of well-known scholars have agreed to attend the meeting, as they acknowledge the usefulness of an event like this in popularising HOM in an important education centre in Asia. These academics, who are attached to a number of Wellcome Trust-funded units, will draw upon an important item of their research - dealing with Europe, North America, Asia and further afield - to develop trans-national perspectives of how to study HOM. This meeting will engender a lot of discussion, which is critically important for an endeavour that seeks to provide new insights to post-and under-graduate teachers about important international developments in the discipline, and the most effective ways of teaching and carrying out research. Themes to be covered: History of pharmacology; Anatomy; Global trade and medicine; Medical genetics and gender; Medicine in the early modern period; Public health in 19th and 20th centuries; Global health programmes and disease eradication; War and medicine; International perspectives on rabies; Scottish doctors and British empire; Obstetrics and surgery; Cross-disciplinary perspectives on leprosy and empire; Hospitals; Medicine and 'witchcraft' in the early modern period; Healthcare in colonial Mumbai/India; Health of industrial labour; Oral histories of contemporary medicine and biological science; History of medical practice and multiple meanings of health.

Amount: £600
Funder: The Wellcome Trust
Recipient: University College London

illustrated lectures to members of the general public - with a direct link to the Wellcome Trust and the Wellcome Collection 16 May 2007

I have been taking my lectures on the History of the Origins of Vaccination to audiences of the general public in recent times, having also addressed meetings and conferences of professional groups for many years. These lectures and talks are based on my researches into the topic. My object in doing this is to make new historical information available to members of the public in an easily understood manner, creating a learning experience which is both interesting and entertaining. The actual and intended audiences include: History Groups, Local History Groups, WI Science Groups, national Women's Register Groups, The University of the Third Age (U3A), Probus, Museum Societies, The NADFAS Associated, Village Residents Societies, Universities, colleges and schools. Collaboration with the Wellcome Outreach initiative has been offered.

Amount: £600
Funder: The Wellcome Trust
Recipient: Misc England

'Developments in mental health since 1945: international and local perspectives' conference to be held at the University of Manchester on 23rd February 2007. 30 Jan 2007

Developments in mental health since 1945: international and local perspectives The workshop will address a neglected period in the history of psychiatry, offer much needed comparative perspectives and provide a forum for historians and practitioners to exchange ideas and develop common understandings. The workshop, which includes both British and North American perspectives, will focus on two main themes. Adult mental health services, with a particular emphasis on the experimental and non-traditional. Changing concepts of and responses to childhood behavioural and emotional disorders. The topics covered are: - Post-asylum geographies of mental illness - Post-war mental health services in Saskatchewan - Radical therapeutic communites post-68 - North Manchester Community Mental Health Services, 1982-96 - Approaches to Maladjusted Children in Britain, 1945-1955 - Child Therapy and Social Welfare 1945-1980 - The Role of ADHD Parent Support Groups in the US and the UK - Changing Accounts of Bad Behaviour in the American Journal of Psychiatry, 1950-2005

Amount: £500
Funder: The Wellcome Trust
Recipient: University of Manchester

Medicine, Astrology and Philosophy in the Pseudo-Galenic De Spermate 29 Aug 2008

The project is collaboration with Prof. Vivian Nutton to examine the philosophical and astrological background of the pseudo-Galenic De Spermate (existing in Latin translation, dated to the thirteen and fourteen centuries). Our specific goals are to evaluate the philosophical and astrological background of the treatise and in particular its Neoplatonic influence; to establish possible Neoplatonic sources; to examine the dialogue between medicine, philosophy, and astrology in the treatise; to assess the attitude toward astrology in the treatise in the context of the traditional antithetical relationship between medicine and astrology and philosophy in Late Antiquity.

Amount: £750
Funder: The Wellcome Trust
Recipient: Florida State University

Role of cell surface proteins in the pathogenesis of Clostridium difficile. 15 Apr 2008

The aim of this project is to define C. difficile genes and gene products essential for adherence to host tissues. The objectives are: 1. To establish a robust model of adhesion of C. difficile to the cultured enteric CaCo2 cell line. 2. To further study adhesion using in vitro organ cultures of hamster gut. 3. To create knock-out mutants of defined genes in C. difficile and to analyse their behaviour in the adhesion models of the bacterium with host tissues. Genes and gene products identified as important for adhesion will be further studied using molecular and biochemical techniques.

Amount: £869
Funder: The Wellcome Trust
Recipient: Imperial College London


Wellcome funding would expand the scope of ‘Asylums, Pathologies and the Themes of Madness’: a one-day symposium to be held at University of Stirling’s Library on January 16th. The symposium is the first step in publicising a Contemporary Gothic archive at Stirling: a resource made possible by recently donated material from both Iain Banks’ estate and Patrick McGrath. We invite academics working on McGrath – and on psychopathology in the Gothic more widely – to view his recently donated materials and to reflect upon the Gothic’s staging of the asylum in light of his fiction. As the son of its last medical superintendent, Patrick McGrath spent his formative years at Broadmoor Lunatic Asylum. The funding would be essential to: Work on cataloguing Broadmoor materials to be put on display at the McGrath symposium. A designated PhD student familiar with the archive – who is studying already local asylum materials from Stirling – would work for 29 hours over 3 weeks (0.27 FTE, £18,031; total cost including holiday pay of £395) to catalogue these materials. Provide travel bursaries to two PhD students working specifically on asylums and the Gothic to attend the conference (£200 total, each travel bursary £100).

Amount: £595
Funder: The Wellcome Trust
Recipient: University of Stirling

Cambridge Research Foray: Film and Population, Cinema as Medicine 30 Nov 2015

The requested small grant would allow me to visit Cambridge University for one week, covering accommodation and sustenance only. There are three goals for this visit: to collaborate with a Cambridge researcher and finalize a paper that considers overpopulation in 1970s cinema; to develop a second, postdoctoral project proposal with a Cambridge professor and make greater collaborative inroads into the History of Science department as well as the Center for Film and Screen; and to further investigate the archival holdings of the Whipple Museum for the History of Science and the Cambridge Medical Library. This work would contribute to two outcomes in the medical humanities: the publication of a peer-reviewed paper on population and cinema; and a postdoctoral project on cinema as medicine. Greater details are to be found below.

Amount: £780
Funder: The Wellcome Trust
Recipient: No Organisation

More Humanity: Christine Borland's translation of empathy in medical anatomy and clinical practice and its incorporation in visual art. 14 Jun 2010

First, the proposed research will examine artist Christine Borland's methodology, focusing on notable artworks made during the last fifteen years. Second, it will analyse how contemporary artworks reference medical history and clinical practices towards providing a renewed direction to advanced artistic practice. The key goals are to record an in-depth interview with Christine Borland, with the production of an interview transcript, and to publish the research findings of the project in a peer review journal.

Amount: £887
Funder: The Wellcome Trust
Recipient: Northumbria University

'Chemistry and pharmacy in the colonial world' to be held at Oxford Brookes University 13th May 2010 18 Jan 2010

Intellectual historians cannot ignore the role played by alchemical practices (experiments, theories, circulation of books and manuscripts, constitution of networks covering the entire European continent and several early colonial settlements) in the agenda of Early Modern learning. Equally, studies published over the last twenty years have much contributed to the appreciation of the role of chemistry in the constitution of research practices in science, technology and medicine, and to the key social and intellectual role played by practitioners of chemistry during the 18th and 19th centuries. Finally, business historians or historians of innovation (including therapeutic innovation) can hardly escape confronting the complex interactions between university and industrial research on a continental and intercontinental level throughout the 20th century. The main goal of the joint Oxford History of Chemistry Seminar series, of which this session is to be a part, is therefore to explore and assert the centrality of the history of chemistry to a variety of research areas dealing with the social, intellectual and economic history of Europe (and beyond) over the last five centuries.

Amount: £600
Funder: The Wellcome Trust
Recipient: Oxford Brookes University

Protein-protein and protein-ligand interactions in the glycolytic pathway. 20 May 2011

T. brucei is a small parasite that causes African trypanisomiasis, commonly known as sleeping sickness, in humans and nagana in cattle in Africa. It has life cycle stages in both the mammalian host and the tsetse fly vector and makes several morphological and biochemical changes when migrating between the two. The mechanisms and control of cell proliferation and differentiation is essential to the life cycle of the parasite and thus understanding the details of these processes is important for the discovery of new drug targets to combat this disease. The genome of T. brucei and other related parasites have been sequenced and many biochemical and genetic tools are available to enable molecular dissection of the genes involved in cell division and differentiation. Previous studies of the structural mechanics of cell division have provided us with some understanding of the temporal and spatial organisation of the cell organelle and cytoskeletal structures [1]. However, much more needs to be understood about the three-dimensional spatial organisation of the cytoskeletal structures and how co-ordination of assembly and cytokinesis is performed in order to better understand the phenotypes presented by the molecular dissection experiments. During my 10 week project I used scanning electron microscopy (SEM), transmission electron microscopy (TEM), immunofluorescence microscopy, and video microscopy to gain more insight into cytoskeletal organisation during cell division, and to compare the processes in the procyclic and the bloodstream forms of the parasite. SEM and video microscopy revealed important differences between the procyclic and bloodstream forms during cell division regarding attachment and growth of the new flagellum, the degree of staggering of the daughter cells during cleavage furrow ingression and the nature of the cytoplasmic connection between the two daughter cells, present just before cell abscission. Fluorescent labelling of ?-tubulin and TEM images provided some evidence for the presence of microtubules in the cytoplasmic connection in the procyclic form, although more evidence is needed.

Amount: £585
Funder: The Wellcome Trust
Recipient: University of Edinburgh

Medical botany in the 19th and early 20th Century: Berthold Carl Seemann (1825-1871)and Melville William Hilton-Simpson (1881-1938). 29 Aug 2014

Visit of Archives in GB, in particular Kew Archives, London, Royal Anthropological Institute of Great Britain, London, Pitt-Rivers-Museum, Oxford. Investigations into the inheritance of Seemann and Hilton-Simpson, screening of letters and documents regarding reports on medicinal virtues and ethnopharmacological uses of plants collected, primarily by botanical interest.

Amount: £873
Funder: The Wellcome Trust
Recipient: Misc Germany

H.M Extension. 31 Aug 2011

H.M.' (working title) is a new performance piece by the award-winning Analogue, following the critically-acclaimed (and Wellcome Trust supported) Beachy Head. We plan to create a new theatre piece telling the story of a man who suffered with both severe long-term memory loss and the inability to form new memories, and the impact the condition subsequently had on both his family and on future biomedical procedures. The R&D for this project is inspired by the famous neuroscientific patient Henry Molaison, who underwent experimental brain surgery in 1953, leaving him with severe retrograde and anterograde memory impairment. Our work investigates the story from three dimensions; at the human scale (H.M.'s day to day encounters, including the story of a relationship vanished from history), at the microscopic scale (the histological mapping of Henry's condition) and the telescopic scale (the global dissemination of the findings, streamed online). This application is to support a process of in-depth research with neuroscientific collaborators, as well as the main period of devising and writing. This phase of work happens prior to rehearsals, performance testing in Germany, and the world premiere of the show at the 2011 Edinburgh Festival, for a significant national audience.

Amount: £600
Funder: The Wellcome Trust
Recipient: Analogue Theatre

Grant to St John the Divine 05 Apr 2018

£966 to commission an independent access audit to inform the new build garden room and accessibility of the church building.

Amount: £966
Funder: City Bridge Trust
Recipient: St John the Divine
Region: London
District: Croydon London Boro

Visualising Illness and Pain. 31 Mar 2016

Drawing on the varied perspectives of artists, historians, art therapists, curators, clinicians and social scientists, the proposed workshop will explore a series of questions relating to the visual representation of illness. Focusing specifically on contemporary works made in response to first-person encounters with illness, the workshop will consider what issues are at stake in reading these artefacts as subjective expressions of pain and suffering. The event will comprise two parts. The fi rst, taking place on a Friday afternoon and evening, will be open to the public, and will include a keynote address by Joanna Bourke and a panel discussion between artist Deborah Padfield, clinician Joanna Zakrzewska and social psychologist Alan Radley. The second, taking place the following day, will take the form of a series of panel discussions involving practitioners from different disciplines, with the aim of addressing a number of clearly defined research questions. We hope that the w orkshop will ultimately function not just as a one-off event, but also as a scoping exercise for a larger collaborative project. One of its likely outcomes will be the planning of an exhibition (with accompanying catalogue) that will be displayed both online and in the Peltz Gallery, Birkbeck.

Amount: £719
Funder: The Wellcome Trust
Recipient: Birkbeck University of London

Experimental Stories: Katy Walker 30 Sep 2015

An AMR scientist with a seemingly unfindable research project is surprised to be recruited to an elite team working to combat the latest suberbug threat. When her home town is quarantined she discovers the government is contemplating unthinkable measures unless she can come up with an alternative. The world has become used to relative health, but most research scientists know how delicate the balance is. This five part thriller shows us what’s waiting around the corner and how we’re going to cope with it.

Amount: £500
Funder: The Wellcome Trust
Recipient: No Organisation

Experimental Stories: Al Smith 30 Sep 2015

"Culture" 3 x 45’ plays

Amount: £500
Funder: The Wellcome Trust
Recipient: United Agents