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Award Year:


Autoimmune disease evaluation 30 Jan 2008

Evaluation of multiplex technology in laboratory diagnosis of autoimmune disease

Children/Young people with duchenn 30 Jan 2008

Transitional Service Framework for Children and Young People with Duchenne Muscular Dystrophy

Low Level Drug Resistant HIV 27 May 2008

Low Level Drug Resistant HIV: implementation of an innovative service

Future Priorities 17 Nov 2008

Integrated Cancer Centre: for future priorities

Anatomical Predictors of aphasia 28 Nov 2008

Identification of Anatomical Predictors of Aphasia Recovery with Diffusion Tensor Imaging

Amount: £193,000
Funder: Guy's and St Thomas' Charity
Recipient: King's College London

Extension application for marketing resource. 16 Jun 2008

Documentary film about the neuropsychology of music. Four nightmarish years of locked wards and shock treatments ended for jazz guitar virtuoso Pat Martino with life-saving brain surgery for an aneurysm, which stripped him of his memory. One of Jazz's greatest exponents was left stranded in a silent wilderness. How then was he able to ascend after fourteen years in the oblivious depths of amnesia to the absolute peak of artistry once more? We must examine the very nature of creativity and the mysterious brain mechanisms underlying the construction of personal identity. What is the self? What changes can it survive?

Amount: £10,000
Funder: The Wellcome Trust
Recipient: Sixteen Films

D'Alembert's Dream - script development. 16 Jan 2008

D'Alembert's Dream - script development and pre-production for a cinematographic adaptation This project aims in the long run to create a film adaptation of Diderot's D'Alembert's Dream, an eighteenth century dialogue creating a delirious universe of scientific speculation and metaphor. One of the main results of the first sciart experimentation phase has been the development from multi-media performance to film and animation. This shift has been motivated by the powerful imagistic references to scientific illustrations, the importance of metamorphosing processes linked to proto-evolutionary ideas and the dream-like, science-fictional qualities which film can transmit more elegantly than theatre. Looking forward into the twenty-first century whilst looking back into the eighteenth century, the idea remains to explore the continuities of an often immaterial and ethically challenging materialism in the context of today's scientific research. This will be done by incorporating into the texture of the film the ideas and visions of contemporary scientists responding to statements in the original text. A dialogue will be created between contemporary innovative science researchers and Diderot's avant la lettre references to evolutionary theory, genetic engineering, cloning, eugenic experiments, chimeras and to the insubstantial nature of consciousness once it has been redefined in the context of materialism. During the next pre-production period towards a film, we will intensify experimentation as regards animation styles, thus developing a unique visual language for D'Alembert's Dream; produce a film script including a new translation of the Diderot text passages, and experiment cinematographically with the involvement of scientists as actors.

"Signalling Sound" to be held at the University of Warwick on 7th March 2009 16 Sep 2008

International Symposium, 'Signalling Sound'

Amount: £4,967
Funder: The Wellcome Trust
Recipient: University of Warwick

Ischia Summer School in the History of the Life Sciences to be held on 28 June to 5 July 2009 29 Aug 2008

Ischia Summer School in the History of the Life Sciences

Amount: £15,280
Funder: The Wellcome Trust
Recipient: University of Cambridge

Psychiatry, murder and M'Naghten in colonial context: The place for forensic psychiatric knowledge in East Africa 30 Jun 2008

This research aims to complement some work I did in Africa in January 2008 on the role and status of psychiatry in the insanity defence in colonial East Africa. The aim of this research is to evaluate the treatment of psychiatric knowledge in murder trials in which insanity defences were raised. This research will include examining trial transcripts, (especially that of Charles Ross; National Archive, CO/533/427/5), as well as medical sources (East African Medical Journal), the press (including trial reports in the East African Standard), and legal sources (especially the East African Law Reports). In addition, there is some archival correspondence at the Wellcome Library (Eugenics Society papers) about a prominent insanity trial from colonial Kenya (Ross, 1932) by the leading East African psychiatrist, HL Gordon, which encapsulated some of his eugenic arguments concerning feeble-mindedness in relation to criminal responsibility. Such sources are not available in Scotland. This research will be presented at both medical history and socio-legal studies conferences, and published in a number of academic journals and in an edited collection. It will form the basis of a larger project on this topic for which I will be seeking funding.

Amount: £3,000
Funder: The Wellcome Trust
Recipient: University of Edinburgh

The performance of medicine : researching the historical writings on the ritual of tarantism. 13 Jul 2008

The project for which this grant is being sought, is for proposed archival research into specific aspects of medical history relating to the phenomenon of tarantism. The grant will allow for detailed examination of documents and sources contained within two libraries, the Wellcome Trust Library, London, and the Bodleian Library, Oxford, both of which hold significant material relating to the historical study of the medical writings concerning tarantism, which date from the 15th Century through to the present. The key goals of this archival research are that it will contribute toward the writing of a monograph, Ritual, Rapture and Remorse: the dance of the spider in Salento, under contract with Peter Lang, which is a study of the history of tarantism through different disciplinary perspectives, and includes discussion of the extensive amount of documentation within the field of the history of medicine. This will make an important contribution to dissemination of these writings, each of which demonstrates the shifts in approaches to the body, medicine and scientific and philosophical paradigms, most particularly in Renaissance and Early Modern Italy, but also moving through to the developments in psychiatric medicine during the 20th Century.

Amount: £1,297
Funder: The Wellcome Trust
Recipient: University of Exeter

A Healthy Market? Health professionals in the advertising of commercial products and services: an exploratory analysis of advertising campaigns in the United Kingdom. 15 Apr 2008

This is an exploratory historical study, using materials archived at the History of Advertising Trust to analyse the role of health professionals and pseudo health professionals in commercial advertising. All media will be included, covering the period from the early 19th century to the present. The study aims to assess the extent of the use of health professionals and pseudo health professionals in advertising campaigns, to explore the range of products and services marketed through this use and to evaluate the nature of the health claims attributed to professionals in these campaigns. The HAT archive will be searched for advertising material from any medium (print, radio, television, film, digital) that relates to products or services marketed to the general public using images or representations of actual or pseudo health professionals Data will be subject to qualitative analysis, using a thematic analysis strategy, to identify the nature of the health claims made and to ascertain the range of products or services advertised using health professionals. Little research has been done on this subject, despite its potential for increasing our understanding of the relationship between commerce and health care, the public image of health professionals or professionals' perspectives on their roles.

Amount: £1,607
Funder: The Wellcome Trust
Recipient: University of East Anglia

'Narration and Medicine in 18th Century Europe' conference to be held at the Maison Française d'Oxford on 18th April 2008. 28 Mar 2008

The eighteenth-century works of fiction we now call 'novels' were a highly reflexive genre. An obvious illustration of this would be the self-reflective tone of the epistolary form, or in first-person narratives. However, the notion of self-reflection was not limited merely to the formal aspect of early novels: European authors themselves constantly tried to define the form they were writing in, often putting forth definitions of it in their prefaces, and in some cases even expounding the narrative structure of their story. Novelists dwelled on narrative structure and at the same time questioned it profoundly, exploring its possibilities and contradictions. Several narrative devices such as authority, the reading contract, and chronological story-telling were investigated and challenged explicitly by writers like Denis Diderot in France (Jacques le Fataliste) and Laurence Sterne in England (Tristram Shandy). Significantly, novelists regularly chose to explore narration through medical thinking. Literary narratives were thus investigated and sometimes revealed through anatomy, descriptions of the living body, or as experimental accounts. This one-day conference will bring together eighteenth-century specialists coming from various disciplines and several European countries to compare the ways in which literature and medical thought use narrative devices in the 1700s. How do novelists use medical thought, and how does it transform their novel-writing? To what purpose did medical writers use narration, and how does it influence their practice and thought? How does eighteenth-century medicine integrate the questions of narrative in its frames) of thought? How does eighteenth-century fiction assimilate illness or epidemics narratives for its own purposes?

Amount: £1,020
Funder: The Wellcome Trust
Recipient: Maison Francaise D'oxford

"Voluntary Action History Society, Third Research Conference" to be held at the University of Liverpool 16-18th July 2008 28 Mar 2008

There is currently considerable scholarly interest in the history of charity and voluntary action. This is not limited either to the United Kingdom or to the concerns of philanthropists and charitable workers; a number recent publications seek to extend the study of voluntary action to new areas and periods, including colonial India and imperial Russia, and other important studies explore voluntary action from the perspective of the beneficiaries of charity. The Voluntary Action History Society Third Research Conference in 2008 aims to build on the interest generated b y recent conferences but also to provide a forum for discussion between scholars working in different chronological periods and in different parts of the world. Papers on medical charities represent the largest single topic area and will represent an important element in the conference, but there will also be presentations that focus on education, families and children, housing, overseas volunteering and international development and the archives and records of charitable organizations.

Amount: £1,000
Funder: The Wellcome Trust
Recipient: University of Liverpool

Global Health Histories/WHO anniversary Lectures, organized in association with the Wellcome Trust and the Wellcome Trust Centre for the History of Medicine at UCL, UK to be held at the WHO in Geneva March to December 2008. 16 Jan 2008

Title of the meeting: 'Global Health Histories/WHO anniversary Lectures, organized in association with the Wellcome Trust and the Wellcome Trust Centre for the History of Medicine at UCL, UK', WHO headquarters, Geneva. This will be the first lecture series of its kind within the headquarters of the World Health Organization in Geneva, Switzerland. The aim is to engage those involved in formulating and implementing health policies with historians of medicine working on policy-related issues, in the expectation that these interactions will be useful to all concerned. The usefulness of historical findings is being increasingly acknowledged within the WHO, as its employees have become more enthusiastic about carrying out more detailed political and social negotiations in the countries and regions where public health and medical schemes are being put into place. The work of the invited speakers is, therefore, likely to be instructive to WHO workers of different ranks and departments, including those seconded to the different Regional Offices on advisory capacities.

Amount: £4,000
Funder: The Wellcome Trust
Recipient: University College London

Promoting Teachers' Understanding of Risk in Socio-Scientific Issues 07 May 2008

The aim of this project is to support and enhance the teaching of the core idea of risk through an innovative approach pioneered in projects aimed at mathematical understanding in the workplace. Mathematics and science teachers will model socio-scientific issues using new technological tools, designed specifically to engage them in consideration of ethical and social issues, building their personal value systems alongside quantifiable mathematical models. By interacting more deeply with interdisciplinary knowledge, we assume that they will be empowered to enthuse their students in meaningful activity around the use of risk. The importance of the discourse of risk in public policy is now being reflected in science and maths curricula but there has been almost no previous pedagogy of risk. This is because understanding risk incorporates concepts which go beyond substantive science or probability into affective and social science domains. To address this problem together with a group of science and maths teachers, we will co-design a computer-based microworld in which teachers can explore and interrogate their knowledge of risk, including pedagogical knowledge, in socio-scientific issues drawn from research. Using this microworld, teachers will generate models that embrace a pedagogy of risk in diverse contexts to increase their own confidence in teaching this important idea and ultimately to enthuse their students. Through regional and national workshops, working within on-line communities, teachers will work with and evaluate these models.

Amount: £122,285
Funder: The Wellcome Trust
Recipient: Institute of Education

Development of a type B lantibiotic for treatment of Clostridium difficile infection 16 Sep 2008

C. difficile infection (CDI) has increased in incidence and severity through the last decade to become the major cause of mortality amongst nosocomial infections. Currently, there are very few therapeutic options for CDI and recurrence of disease after initial successful therapy is a major health problem and burden to healthcare systems.

Amount: £3,500,000
Funder: The Wellcome Trust
Recipient: Novacta Biosystems Ltd

Centre of excellence in Public Health Research. 16 Sep 2008

Tackling the complex and inter-related root causes of public health problems requires systems approaches which recognize that the whole is often greater than the sum of the parts. More dynamic and effective relationships are needed between public health scientists, policy makers, practitioners and local communities, and a move away from an outdated linear model of passive knowledge transfer to one that recognizes that knowledge is both explicit and tacit, and generated by multiple stakeholders. Thus, the Queen's University Belfast (QUB) and the Institute of Public (Health in Ireland (IPH), in partnership with the Regional Health and Social Care Authority and the Community Development and Health Network, intend to establish a CoE for Public Health Science Research as part of a networked cluster of Centres across the country that will strengthen capacity for research and practice to improve the health of the UK population. The Centre will foster a multidisciplinary approach to research and training and the translation of research into policy and public health practice. The priority will be to use the unique opportunities that exist in Northern Ireland, with its distinctive approach to integrated health and social services and well connected civic and public sector structures, to research the social and biological causes of chronic disease and the main causes of inequalities in health experienced in the UK.

Amount: £189,044
Funder: The Wellcome Trust
Recipient: Queen's University Belfast

Enabling Public Health Foundation of India's Network of Indian Institutes of Public Health. 14 Apr 2008

Broadly, the desired outcomes to which this strategic award will contribute include: - Eight IIPHs created over the course of the next 8 years with each demonstrating active faculty, teaching and research programmes, an effective public health advocacy and health policy role, relationships to enable research across priority areas, including state and central government, multi- and bilateral agencies, academic institutions and civil society agencies - A multidisciplinary cadre of public health professionals and practitioners developed and working within IIPHs. Over the 5 years of this proposal, a majority of the faculty in each of the first three IIPHs that are now planned to open between July 2008 and July 2009, will be trained and strengthened. It is expected that each IIPH will start with a complement of 20 faculty, growing to about 70 faculty at full strength - IIPHs with collaborative research programmes, Masters courses underway, a range of other training courses, formal lin kages with local government, health services and NGOs, scientific output, and a sustainable and growing number of high quality students registered for training

Amount: £2,706,350
Funder: The Wellcome Trust
Recipient: Public Health Foundation of India