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The Big Move 05 Jan 2012

Funding under Sport England's Inspired Facilities funding programme for a Capital project titled 'The Big Move'. This project lists its main activity as Gymnastics. This funding has contributed towards a Gymnastics Centre - Gymnastics Centre (Gynmastics Centre)

Amount: £40,000
Funder: Sport England
Recipient: Holeach & Fenland Gymnastic Club
Region: East Midlands
District: South Holland District

Prison Reform And Better Outcomes For Prisoners And Their Families - The Big Red Food Shed 01 Apr 2016

Social enterprise Community food growing enterprise

Amount: £71,689
Funder: Ministry of Justice
Recipient: The Big Red Food Shed

Frome Childrens Festival program 10 May 2016

Children's festival activities programme

Amount: £500
Funder: Somerset Community Foundation
Recipient: Young People Frome

Goldies Singing in Taunton 24 Jun 2016

Singing sessions for older people.

Amount: £660
Funder: Somerset Community Foundation
Recipient: Golden Oldies

Hall improvements 19 Jul 2016

Village hall improvements

Amount: £1,100
Funder: Somerset Community Foundation
Recipient: Jubilee Hall , Ditcheat

Holiday Hunger 2019 19 Jul 2019

Food bag collections

Big Fish 117 Excellent Project 27 Nov 2013

Funding under Sport England's Small Grants funding programme for a Revenue project titled 'Big Fish 117 Excellent Project'. This project lists its main activity as Multi Sports.

Amount: £6,075
Funder: Sport England
Recipient: Big Fish 117 Ministries
Region: South East Coast
District: Surrey Heath District

Bug Club 26 Jul 2012

Funding under Sport England's Small Grants funding programme for a Revenue project titled 'Bug Club'. This project lists its main activity as Sailing & Yachting.

Amount: £10,000
Funder: Sport England
Recipient: Worthing Sailing Club
Region: South East Coast
District: Worthing District

The Boathouse Big Clean up ! 04 Feb 2016

Funding under Sport England's Flood Relief Fund funding programme for a Revenue project titled 'The Boathouse Big Clean up !'. This project lists its main activity as Multi Sports. This funding has contributed towards a Flood Relief - Flood Relief (Repair/Defence)

Amount: £1,240
Funder: Sport England
Recipient: Burnley Leisure
Region: North West
District: Burnley District

Research to venture mental health programme: Stream 3 (BGV) 30 Sep 2018

This programme will bring together the expertise and track record of Zinc (venture incubation), Bethnal Green Ventures (venture acceleration) and Big Society Capital (social impact investing) to innovate and try new ways of working, by testing the best ways to support and finance ventures that seek to improve people’s mental health in response to their real needs and to ensure they are people-centred and research-led. The programme will also consider how research and evidence can shape funding and co-financing models and find out whether there are systematic gaps or approaches that arise from the learnings. There will be four streams of work: 1) Understanding the needs and barriers for scale within mental health-related charitable organisations (run by BSC) 2) Co-creating mental health ventures at initial ideas stage (run by Zinc), 3) Providing funding at a beta stage (run by BGV) and 4) Conclusions, evaluation and dissemination of learning (coordinated by BSC)

Amount: £134,500
Funder: The Wellcome Trust
Recipient: Bethnal Green Ventures

Molecular and antimicrobial characterisation of Propionibacterium acnes isolates from patients with severe recalcitrant papulopustular and nodular acne 31 May 2018

The widespread use of antibiotics for the treatment of acne vulgaris has led to the selection of Propionibacterium acnes ‘super-bug’ strains that are now resistant to first line antibiotics. Consequently, a growing number of patients are emerging with forms of acne that are non-responsive to common antibiotic therapies. As alarming, many of these patients also have extremely severe and aggressive forms of the disease, as well as resistance to oral retinoids. Characterization of the P. acnes population associated with severe recalcitrant papulopustular and nodular acne is therefore vital so we can identify new, pathogenic, multi-drug resistant lineages that may be driving this pathology. Such a study will also enable us to investigate if novel super-bug lineages of this bacterium are disseminating within the population, as well as providing an invaluable platform for the generation of skin microbiome-based diagnostics. The aim of this project will therefore be to characterize antibiotic resistant isolates of P. acnes recovered from patients with severe recalcitrant papulopustular and nodular acne, and a key goal will be to determine if strains represent new genetic sequence types circulating within the population. Another key objective will be to examine minimum inhibitory concentrations (MICs) and biofilm formation by these strains.

Amount: £0
Funder: The Wellcome Trust
Recipient: Ulster University

Towards salary costs, helping the homeless in Swindon 04 Feb 2014

Towards salary costs, helping the homeless in Swindon.

Amount: £1,500
Funder: Woodward Charitable Trust
Recipient: Big Breakfast +
Region: South West
District: Cotswold District

Costs setting up a Little Brum Youth Theatre 30 Jul 2008

Towards the costs setting up a Little Brum Youth Theatre for children aged 8-12 from across the West Midlands for out of school artistic and educational provision.

The Big Issue Foundation - 2 27 Nov 2013

Hardship Fund

Amount: £1,500
Funder: London Catalyst
Recipient: The Big Issue Foundation
Region: London
District: Islington London Boro

MUGA (2 pitches, one floodlit) 11 Aug 2017

Funding under Sport England's Community Asset Fund funding programme for a Capital project titled 'MUGA (2 pitches, one floodlit)'. This project lists its main activity as Multi Sports. This funding has contributed towards a MUGA - MUGA (Informal Recreation)

Amount: £100,000
Funder: Sport England
Recipient: St Matthews Big Local (Leicester)
Region: East Midlands
District: City of Leicester

Dream Fitness Dance 21 Dec 2017

Funding under Sport England's Small Grants funding programme for a Revenue project titled 'Dream Fitness Dance'. This project is a Exercise & Fitness project, with a focus on younger beneficiaries.

Amount: £9,787
Funder: Sport England
Recipient: Dream Big Sports LTD
Region: North West
District: Oldham District

MetaboFlow - the development of standardised workflows for processing metabolomics data to aid reproducible data sharing and big data initiatives 16 Jun 2016

The processing and analysis of mass spectrometry and nuclear magnetic resonance spectroscopy data in metabolomics is largely performed on an individual basis following local laboratory methodologies. Metabolomics lacks reproducible computational workflows based on internationally accepted standard operating procedures and this is impacting on the field in terms of reproducibility of studies and subsequent sharing of data. Furthermore, with improvements in reproducibility in analytical equipment, individual laboratories are acquiring larger, more complex datasets, which are a significant challenge to process. We propose to build, test and deliver the cloud-based Galaxy workflow, MetaboFlow, which will have computational capacity to process datasets with 1000s of samples and simultaneously capture all metadata associated with the users’ data processing workflow to allow rigorous reproducibility. We will formulate the workflow using several popular processing, feature extraction and compound identification tools and provide functionality to readily use on-line databases including our international repository, MetaboLights. The tools will be selected based on our current survey of the international metabolomics community. This proposal is a re-submission following consultation with the Trust. Specifically we have developed and implemented a plan to capture the communities’ needs, and have made significant cost savings by integrating our work with other initiatives using Galaxy.

Amount: £190,915
Funder: The Wellcome Trust
Recipient: University of Birmingham

Developing Excellence in Leadership and Genetic Training for Malaria Elimination in Sub-Saharan Africa (DELGEME) 05 May 2015

Despite recent important progress in decreasing malaria burden around the World, globally, an estimated 198 million cases of malaria occurred globally in 2013, leading to to 584 000 deaths. The burden is heaviest in sub-Saharan Africa, where an estimated 90% of all malaria deaths occur, and in children aged under 5 years, who account for 78% of all deaths. [WHO 2014]. The high level of diversity of malaria parasites in the African continent contravenes elimination strategies and sustains the high burden of the disease in Africa. Knowledge of the genome wide diversity of the parasite, gene flow and adaptive processes are required to develop and refine elimination strategies. Indeed, the confirmation of Plasmodium falciparum artemisinin resistance in South-East Asia calls for pre-emptive surveillance of African parasite populations for genetic markers of emerging drug resistance. Because of unprecedented technological advances, there is a sharp increase in the production of genetic data from a range of pathogens including malaria parasites. Yet, very little of these thousands of terabites of sequence data has been translated into knowledge relevant for malaria control. This is mainly due to the fact that there is a "strong wall" between the malaria control community and the geneticists, indeed the two groups hardly understandeach other's languages. We propose to "tear down this wall". Indeed the translation of these genetic sequences into knowledge requires cutting edge skills that are currently lacking in sub-Saharan Africa. Yet, genetics is increasingly required for decision making in major public health threats such as HIV/AIDS, Tuberculosis, Malaria and other tropical diseases. To address this gap, a couple of years ago we established an African-led consortium, the African Plasmodium Diversity Network (PDNA) [Ghansah et al. Science]. PDNA includes Research and Academic Institutions from fifteen countries in sub-Saharan Africa. Through this DELTAS Africa proposal, which is driven by the PDNA leaders, will primarily focus on bridging the gap between public health community and geneticist through effectively engaging health workers and communities to interact with relevant genetic information. The main aims of this training programme will be to (1)Train, retain and develop graduates,doctoral and Postdoctoral fellows on genomics and bioinformatics across malaria endemic countries and (2) Develop programs to enhance the understanding and dissemination of genetic data relevant to malaria interventions and eradication programmes. Short-term training will be delivered for PDNA fellows including public health officers on genetics, clinical studies, ethics, grant writing, grant management and student supervision. Formal long-term curricula (big data science, biostatistics, health informatics, genomics, cell biology, molecular biology and bioinformatics) will be designed and implemented with contribution and oversight from a wide range of local and International Faculty and relevant advisory boards. Trainees already familiar with or actively involved in disease control will be targeted for recruitment. Customized career development and mentorship of targeted scientists will reveal and nurture new leaders in these specific fields.We will increasing the number of skilled Africans capable of leading the field and fulling exploiting genetics for the improvement of health in Africa.

Amount: £905,541
Funder: The Wellcome Trust
Recipient: Mali Service Centre

Exploring the feasibility of school based interventions to reduce sugar sweetened beverage consumption in India 17 Nov 2014

Sugar-sweetened beverage (SSB) consumption is established as a major risk factor for overweight and obesity, as well asan array of cardio-metabolic conditions, especially type 2 diabetes and dental caries. SSB consumption is particularlypopular in school going children. In the past few decades, sources of energy intake among youth have shifted towardgreater consumption of sugar-sweetened beverages (SSBs), such as soda, sports drinks, and high calorie fruit drinks. Thisshift has important public health implications given that SSB consumption has been associated with youth obesity andweight gain, which have several physical and psychosocial consequences. This becomes a very serious problem especiallyfor Low and middle Income Countries (LMICs) which are demographically very young. In certain countries including Indianational taxation policies have been introduced to promote healthy diet such as a tax on sugary soft drinks but thesepolicies have focussed primarily on soda while not taxing other SSBs. As an alternative to a national tax policy, there is the option of implementing pricing policy at a more local level through a settings approach. Some schools have also takenvoluntary action restricting the sales of soda but have left out other SSBs and have shown a mixed bag of results providing no clear evidence on the best set of interventions which can lead to reduction in SSB consumption among youth. The development, implementation and evaluation of a fiscal and policy intervention to reduce SSB consumption amongst school going children is a complex and challenging task. Before a full scale randomised controlled trial can be undertaken detailed preliminary research is needed. This study therefore proposes to undertake a two-phased investigation to inform and test the acceptability and feasibility of a SSB fiscal and policy intervention delivered in the setting of recognised non-aided public schools of New Delhi.

Amount: £21,451
Funder: The Wellcome Trust
Recipient: Public Health Foundation of India

Criminel - The hotel case. 14 Apr 2014

How it works? Uniquely, this game is a fully 3D, environmental exploration and investigationgame for iPad, with a cool photography mechanic using the gyroscope and accelerometer. This interface will create the sensation of holding a big, old camera and taking well-exposed, steady photos to be used for the second act. Wherever you turn and point the iPad is where the player in the virtual world will look, with a simple swipe bringing out the large format, turn of the century camera, ready to take a photo. Both intuitive and fun, the mechanic recreates the sensation of investigating and opening up a space, while also posing the forensic challenge of finding and focusing on the clues crucial forthe case.

Amount: £25,000
Funder: The Wellcome Trust
Recipient: 4PM Game Limited