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Funders:
Paul Hamlyn Foundation
The Wellcome Trust
Devon Community Foundation
Award Year:
2017

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Results

Vacation Scholarships 2017 - Royal College of Surgeons in Ireland 16 Jun 2017

<p>Vacation Scholarships 2017 - Royal College of Surgeons in Ireland</p>

Amount: £6,000
Funder: The Wellcome Trust
Recipient: Royal College of Surgeons in Ireland

META-DAC - Managing Ethico-social and Technical issues and Administration of Data Access Committee 15 May 2017

<p>We propose establishing a multi-agency data access committee (the META-DAC) to service several of the nation&rsquo;s major cohort studies and to provide a scalable mechanism to incorporate additional cohorts in the future. From 1 May 2015, the META-DAC will manage and provide decisional oversight of access by researchers and other bona fide professionals to data and biosamples held by the initially designated studies: 1958BC, 1970BC, Millennium BC and Understanding Society and, initially as a pilot of scalability, incorporation of the English Longitudinal Study of Ageing (ELSA). The META-DAC will develop, implement and maintain all administrative and technical activities plus policies needed to realise an access mechanism that is fit for purpose given the complex biomedical/social data and samples in question. It will audit its own activity and provide regular feedback to funders and individual studies.</p>

Amount: £68,888
Funder: The Wellcome Trust
Recipient: Newcastle University

CHIM - Shigella sonnei in Vietnamese adults - Development funds 17 Nov 2017

<p>Diarrhoea remains a major cause of childhood morbidity and mortality globally. The vast majority of the 2 billion<br> annual diarrhoeal infections occur in low and middle-income countries (LMICs). Members of the genus <em>Shigella</em><br> are key agents of diarrhoea in LMICs, and <em>S. sonnei </em>is replacing <em>S. flexneri </em>as the predominant species globally.<br> There is a necessity to improve our knowledge of <em>S. sonnei</em> infections in LMICs, with a specific requirement to<br> better understand host-pathogen interactions and the natural history of disease in a setting where the organism<br> is well understood, well described, and associated with a significant disease burden. Therefore, we aim to<br> establish a Controlled Human Infection Model (CHIM) of <em>S. sonnei</em> diarrhoea in healthy Vietnamese adults.&nbsp;</p> <p>&nbsp;</p> <p>This is an innovative project will be the first CHIM study conducted at the Vietnam MOP.&nbsp; Therefore, it is imperative that the project is carefully designed in consultation with all relevant stakeholders. In order to ensure that the proposal is developed to the required standard in the timeframe available, I am requesting funds to employ an international postdoctoral assistant, with a background in microbiology and clinical research on a consultancy basis.&nbsp;</p>

Amount: £21,120
Funder: The Wellcome Trust
Recipient: University of Oxford

Malaria Controlled Human Infection Model - application development 17 Nov 2017

<p>We wish to apply for funds to develop the malaria CHIM application. These are for a Co-investigators/stakeholders meeting to be held in Bangkok, Thailand, on 30<sup>th</sup> and 31<sup>st</sup> January 2018 and to support a writing meeting of the PIs in February 2018 in Kilifi, Kenya.</p>

Amount: £22,186
Funder: The Wellcome Trust
Recipient: University of Oxford

UCL Unit for Stigma Research: Advancing theory and practice in the stigma field 04 Dec 2017

<p>Our new UCL Unit for Stigma Research (UCLUS) will be a hub for innovative high quality research and theory production in the field of stigma research.&nbsp;UCLUS brings together research across diverse fields, including intellectual disability, mental health and dementia, and&nbsp;explores cross-cutting themes and opportunities for research. We are seeking funding to support UCLUS activities and explore areas for new research on stigma resistance and disclosure decision making, two&nbsp;novel areas in which we are piloting work.&nbsp;A better understanding of what makes some members of highly stigmatised groups more vulnerable/resistant to stigma, and how they manage disclosure offers the potential for innovative contributions&nbsp;to broader theorising on responses to adversity. It can also inform the development of interventions that enhance wellbeing via capacity to resist stigma among members of highly stigmatised groups. Funding will allow us to (a) explore this area further, (b) develop&nbsp;a research agenda, (c) build capacity for high quality research, and (d) extend existing&nbsp;and form new partnerships to&nbsp;take this work forward through the public launch of UCLUS,&nbsp;a seminar series, development of the research unit's social media presence, a UCLUS led session at the 2018 IASSID European Congress, and international collaborative visits.&nbsp;&nbsp;</p>

Amount: £29,633
Funder: The Wellcome Trust
Recipient: University College London

Northern Bioethics Network: Linking institutions to build bioethics capacity in the UK north 04 Dec 2017

<p >We aim to create an inter-institutional Northern Bioethics Network of academics in bioethics across the UK North. The objective of the Network is to enable bioethics researchers, who may be few in number within their own institutions, to form a connected regional research community that can promote capacity-building; career development; collaboration; and innovation in scholarship and engagement in bioethics.</p> <p >The formation of a geographically-linked Network is particularly important because while institutions in the southern UK enjoy relative proximity and are thus able to benefit more easily from local inter-institutional research strengths, harnessing the more widely-dispersed capacity for inter-institutional synergy in the north requires additional support to facilitate networking and collaboration, in order to promote inclusion of diverse regional perspectives.</p> <p >An important component of building and maintaining such a Network is the opportunity for in-person interactions, to build professional relationships across time and between researchers at different career stages. The funding requested in this Small Grant will allow us to hold three in what is intended to be an ongoing series of bi-annual meetings rotating amongst host institutions. These first few meetings will provide an initial impetus to help establish the Network, creating momentum to enable us to build longer-term sustainability.</p>

Amount: £10,785
Funder: The Wellcome Trust
Recipient: University of Edinburgh

Dengue Controlled Human Infection Model - Development Grant 17 Nov 2017

<p>Following a positive response to the&nbsp;preliminary submission for grant funding&nbsp;to&nbsp;establish a Dengue Controlled Human Infection Model (Dengue-CHIM )&nbsp;in Ho Chi Minh City, Vietnam, I am submitting this request&nbsp;for a small grant&nbsp;to assist in refining and&nbsp;developing the main proposal prior to&nbsp;final&nbsp;submission in March 2018.</p> <p>&nbsp;</p> <p>During this pre-submission phase I plan to employ an experienced&nbsp;post-doctoral immunologist to carry out a) a scoping review of the current landscape of dengue vaccines in development, and b) a review exploring the&nbsp;current understanding of the immune response to/protection from&nbsp;DENV infection and disease, particularly focusing on&nbsp;immune correlates of protection.&nbsp;</p> <p>&nbsp;</p> <p>This will be the first application of a Dengue-CHIM approach in any dengue&nbsp;endemic setting, and&nbsp;raises a number of important bioethical&nbsp;concerns. Therefore I also plan to employ a Vietnamese social science research assistant for a period of 4 months&nbsp;to engage with&nbsp;key Vietnamese stakeholders to discuss the important issues surrounding endemic setting&nbsp;CHIMs,&nbsp;conduct preliminary informal interviews with these individuals, and help to develop the agenda for&nbsp;a 2 day &nbsp;workshop&nbsp;focused on Bioethics and Stakeholder Engagement related to endemic setting CHIMs that will take place in early March.<br> &nbsp;&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p>

Amount: £23,690
Funder: The Wellcome Trust
Recipient: University of Oxford

Crafting Qualitative Health Research for the Future 04 Dec 2017

<p>Healthcare environments across the globe are encountering new challenges as they respond to changing populations, global austerity, rapid technological advances, personalised medicine, and demands for more patient involvement. We believe that qualitative health research (QHR) can contribute to our understanding and responses to these challenges, and we have developed a proposal which aims to expand and improve the work of this field. This proposed work will be conducted through our UCL Qualitative Health Research Network (QHRN) and will include the following activities: 1) a networking and brainstorming event to create a forum for the critical analysis and improvement of QHR; 2) the fourth QHRN symposium, a two-day event with 200 delegates, 20 oral presentations and 40 posters; and 3) our quarterly seminar series, which showcases presentations from leading scholars in QHR. The main outputs generated through these events and activities will include: A position paper detailing recommendations for the improvement of QHR, publication of our proceedings from the symposium in a peer-reviewed journal, workshops and other training opportunities at the QHRN Symposium, the continuation of communication channels for members of the network (website, email listserv, and Twitter account), and dissemination of findings of QHR to patient organisations, practitioners and policymakers.</p>

Amount: £29,198
Funder: The Wellcome Trust
Recipient: University College London

Health for All in An Unequal World: Obligations of Global Bioethics 04 Dec 2017

<p>Despite several gains in health research and healthcare, global health insecurity is a formidable challenge for the health and bioethics communities. The public health crisis due to Ebola, Zika, and the conflict induced devastations across the globe, for instance, are testimonials of these realities &ndash; the inequities, the poor plight of national as well as global health systems, their preparedness and the ethical issues therein. &nbsp;&nbsp;&nbsp;</p> <p>Given this, the 14<sup>th</sup> World Congress of Bioethics (WCB) by the International Association of Bioethics, scheduled during 4-7 December 2018 in Delhi, India is being organized by Sama Resource Group for Women and Health and Forum for Medical Ethics Society on the theme of &ldquo;Health for All in An Unequal World: Obligations of Global Bioethics&rdquo;. &nbsp;The Congress will establish &nbsp;deeper synergies between multi-disciplinary constituencies towards strengthened ethical practice, policy, law in the context of Health for All. Activities leading to and during the Congress will enable mobilization,&nbsp;skill building and networking, particularly of the next generation of South-Asian bioethicists and provide a platform for intersectional dialogue. A spectrum of sub thematic areas drawn from the main Congress theme will be discussed at the Congress.</p>

Equator From The Air 28 Nov 2017

<p>We plan to make a four part television series for the BBC entitled &quot;Equator From The Air&quot;.&nbsp; It has been commissioned by the BBC,&nbsp;and is slated for broadcast on BBC Two in early 2019, in a primetime slot.&nbsp; The series will see television presenter Gordon Buchanan will travel around the Equator.&nbsp; It will be an accessible and beautiful series with an emphasis on aerial photography, but the substance will be Gordon exploring how the world is changing through the eyes of scientists and locals.</p> <p>The series will contain a mix of stories about wildlife and people.&nbsp; 25 minutes of content across the series&nbsp;would explore issues relating to human health.&nbsp; We have been working with Sophie Tunstall-Behrens of the Our Planet Our Health team, who has put us in touch with several scientists whose work we&nbsp;intend&nbsp;to feature in the finished programme.&nbsp; We fully expect that the series will raise awareness of how climate change is currently affecting human health, vulnerable communities and wildlife.</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p>

Controlled Human Infection Models Development Funds UNS58184 17 Nov 2017

<p>The Wellcome CHIM team have invited a Development Award application in the preparation of the full Malawi Accelerated Research in Vaccines by Experimental and Laboratory Systems (MARVELS) grant.</p> <p>&nbsp;</p> <p>The Blantyre international workshop &ldquo;CHIM in LMIC&rdquo; (May 2017) identified key areas for MARVELS to address before set-up.&nbsp; These were:</p> <ol> <li>Acceptability, ethics and governance</li> <li>Laboratory systems for inoculum preparation and detection</li> <li>Clinical systems for recruitment, safe inoculation and close follow-up.</li> </ol> <p>This workshop published proceedings which further detailed the tests to be applied in each of these domains, and form the basis of this application for a Development Award (Wellcome Open Research 2017;2:70).&nbsp; This Development Award will address the three main areas identified by the Blantyre workshop in order to <u>mitigate the set-up risks of MARVELS Phase 1 on which the whole programme depends</u>.</p> <p>&nbsp;</p> <p>&nbsp;</p>

Amount: £11,140
Funder: The Wellcome Trust
Recipient: Liverpool School of Tropical Medicine

A realist review of community engagement with health research 07 Dec 2017

<p>The project will conduct a comprehensive review of community engagement using a realist review approach appropriate for tackling the conceptual complexity and practical diversity of the field. A review team with worldleading expertise in the theory and practice of CE will be supported by an advisory panel of internationally renowned realist review scholars. The review will begin with engagement with malaria research as a &lsquo;pathfinder&rsquo; topic &ndash; and draw on a network of content experts, implementers and funders to input into and validate the review, ensuring its findings are widely disseminated and embedded in international CE work.</p> <p>Wellcome, BMFG and leading global health funders and implementation partners will benefit from a consolidated evidence base to underpin development of CE strategies in global health research and interventions. Outputs will include articles in peer reviewed open-access journals, an accessible evidence base on MESH/HELP, including context-relevant guidance for developing and evaluating CE strategies, and a critical mass of academics, practitioners, implementers and funders with a mutual interest in strengthening the theory and practice of engagement. In this way the review will spearhead the beginnings of a &lsquo;science&rsquo; of community engagement and outline a clear value proposition for CE in global health research (14).</p>

Amount: £260,250
Funder: The Wellcome Trust
Recipient: University of Oxford

A Case for the Ordinary: The Patient Experience of Mental Health Care in Staffordshire, 1818-1960 16 Nov 2017

<p>This innovative cataloguing project&nbsp;will make accessible&nbsp;case notes of&nbsp;38,000&nbsp;patients treated in Staffordshire's three County Asylums, from 1818 to&nbsp;1960. Collaboration with academic partners&nbsp;at the concept stage has&nbsp;ensured that&nbsp;research imperatives are addressed, with a particular emphasis on access to information in 20th-century patient records. The resources produced will be an open catalogue of early patient case files and a database of extracted information from case files less than 100 years old, the latter available through a simple access process agreed with our NHS Trusts.&nbsp;The method of cataloguing will permit a rolling programme of uploading&nbsp;newly open data to the&nbsp;catalogue and the ongoing involvement of our project advisory board will ensure that the resources&nbsp;have a&nbsp;wide academic reach.</p> <p>&nbsp;</p> <p>The breadth, completeness and representativeness of the Staffordshire collection and the resources produced by this project&nbsp;will&nbsp;offer&nbsp;a unique&nbsp;opportunity to interrogate data&nbsp;from patient case records&nbsp;for specific themes over an unprecedentedly long period. Staffordshire saw pioneering approaches in&nbsp;mental health care&nbsp;but conversely these records also provide an exceptional resource for studying the experience&nbsp;of&nbsp;ordinary English provincial patients at multiple sites&nbsp;over the broad sweep of public asylum history.&nbsp;</p>

Amount: £167,519
Funder: The Wellcome Trust
Recipient: Staffordshire County Council

Unlocking the Science Museum’s GM Archives: revealing the evidence, informing the debate 16 Nov 2017

<p>The Science Museum wishes to maximise the potential of our GM (Genetically Modified)&nbsp;archives to inform, inspire and engage our audiences. Currently there is very basic information in our archives catalogue, but the vast majority of the material is undocumented and therefore inaccessible. The Museum does not currently have the&nbsp;resources to enable the cataloguing and processing work needed. Therefore to achieve our vision we are seeking a grant to create a coherent, cross-referenced catalogue of the collections, digitise the analogue media, and preserve the holdings through repackaging into archival grade materials.</p> <p>This project offers solutions to several challenges including the inaccessibility of the information, the need for the Museum to contribute to ongoing public debate on gallery and through social media and the potential support this archive could be lending to our own and other research projects.</p> <p>The Science Museum is developing content for a new contemporary agriculture gallery and the GM debate is an obvious key theme. If these archives could be unlocked and interpreted they could inform content development and public events. There would be significant potential to use this material to&nbsp;benefit not just the Museum, but also historians, scientists, policy makers, planners and the public</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p>

Amount: £17,588
Funder: The Wellcome Trust
Recipient: Science Museum

40 years of IVF History: Opening up Access to the Louise Brown Archive 16 Nov 2017

<p>The Louise Brown collection at Bristol Culture documents the birth and life of Louise Brown, the first baby born following conception by in vitro fertilisation, and her parents Lesley and John.&nbsp; A number of academics working on research projects in the field are interested in accessing the material, which crosses the boundaries of medical and social sciences. 2018 also marks the 40th anniversary of Louise&rsquo;s birth, and we anticipate wider demand for the material as a result, particularly given an exhibition on IVF proposed by the Science Museum.</p> <p>Our overarching goal is to open up these records for research, to&nbsp;be achieved&nbsp;by:</p> <p>&bull;&nbsp;professional cataloguing of archive and museum items, after which they will be available for public consultation in Bristol and for loan to the Science Museum<br> &bull;&nbsp;repackaging, preservation and conservation work to ensure access to the material long term<br> &bull;&nbsp;digitisation of audio-visual items which are currently inaccessible owing to their format and liable to deterioration<br> &bull;&nbsp;publicity to raise awareness of the catalogued collection via links with other archives and research centres<br> &bull;&nbsp;a display of selected material in&nbsp;permanent galleries at&nbsp;Bristol Culture's M Shed museum, launched by a public event with&nbsp;Louise Brown.</p>

Amount: £15,671
Funder: The Wellcome Trust
Recipient: Bristol City Council

Royal Botanic Gardens, Kew Miscellaneous Reports cataloguing & conservation project 16 Nov 2017

<p>The project goals are to conserve and catalogue a series of 771 volumes, The Miscellaneous Reports, held in the Archives of the Royal Botanic Gardens, Kew. The Reports collate unique archive and printed material relating to the administration of the British colonial botanic gardens and stations during the nineteenth and early twentieth centuries. They document the economic botany of these regions through correspondence with Kew, printed reports, newspaper articles, and illustrative material such as maps, photographs and sketches. Potential research themes include indigenous use of plants, medicinal use, history of science, environmental history, nutrition and health, anthropology, ethnography and agricultural history.</p> <p>The project aims to catalogue them into Kew's on-line Archive Catalogue. Other than a listing of the titles of the volumes, the collection is uncatalogued. Two conservators will rehouse and repair volumes so they can be safely handled. An archivist will be employed to catalogue the papers, including people, places, plant names and subjects, making this underused and unknown body of material accessible to the research community. The Wellcome Trust-funded Scoping Report (2015) identified that researchers were unaware of the collection or its contents, so making it accessible would enable primary research of a previously unknown resource to occur.</p>

Amount: £152,005
Funder: The Wellcome Trust
Recipient: Kew Royal Botanic Gardens

Cataloguing the Freud Museum Archives Phase II 16 Nov 2017

<p>The Freud Museum archive comprises an important collection of material relating to the history and development of psychoanalysis. Approximately half of the collection has been catalogued to archival standards thanks in part to previous funding from the Wellcome Trust and Arts Council England. We are now seeking to catalogue the remainder. The project goals are:</p> <ul> <li>To catalogue to best practice standards the remaining uncatalogued archive holdings at the Freud Museum, including original correspondence and manuscripts of Sigmund Freud, documents of Dorothy Burlingham (Anna Freud&rsquo;s lifelong colleague and companion), papers from the early days of Vienna Psychoanalytic Society and British Psycho-Analytical Society, additional documents that complement the collections of Anna Freud and S&aacute;ndor Ferenczi papers, and documents and photographs relating to other members of the Freud family and staff. This will result in a complete archive catalogue.</li> <li>To repackage archive collections in appropriate materials.</li> <li>To complete&nbsp;urgent conservation work.</li> <li>To make the archive catalogue available online on the Freud Museum Website and via the Archives Hub (the Jisc-funded online gateway to over 300 UK archives).</li> <li>To put in place updated plans and policies for archive documentation standards, care and conservation going forward.</li> </ul>

Amount: £22,667
Funder: The Wellcome Trust
Recipient: Freud Museum London

Opening Up the Body: The Post Mortem Case Books of St George's Hospital 16 Nov 2017

<p>The <em>Opening Up the Body</em> project aims to conserve the Post Mortem Examinations and Case Books of St George&rsquo;s Hospital, 1841-1946, and to catalogue and digitise those dating from 1841-1917 (see ethics section for details). This will enable access for academic research and public engagement activities. These historical records, which chart the golden age of the post mortem, from its heyday in the 19<sup>th</sup> century to its subsequent decline in the second half of the 20th century, will be made accessible in partnership with the London Metropolitan Archives (LMA) and the Leather Conservation Centre (LCC).<br> <br> Conservation of the leather will be undertaken by the LCC, and digitisation and minor repairs of the text block will be carried out by LMA&nbsp;in their dedicated studios. Two project archivists, based at St George's, University of London, will catalogue the collection under the supervision of the university archivist. The catalogue data and digitised images will be searchable through AtoM (Access to Memory) software and will be available on the St George&rsquo;s, University of London website. The collection will be promoted through a number of relevant archive and medical humanities networks to increase accessibility to academic researchers and other interested parties.</p>

Amount: £159,862
Funder: The Wellcome Trust
Recipient: St George's University of London

Challenging Archives: Delivering research access, public engagement and the curatorial care of the Franko B Archive 16 Nov 2017

<p>In consultation with the artist, this project will&nbsp;catalogue and conserve&nbsp;his unique, research-rich&nbsp;archive and make it&nbsp;&nbsp;accessible to meet established&nbsp;demands for research and public dissemination.&nbsp; The nature of the documentation, however, presents a set of particularly complex&nbsp;legal, ethical and practical challenges for archival and museological practice.&nbsp; These challenges, reflecting FB&rsquo;s work, are interdisciplinary, and run parallel to those faced by other medical and LGBT+ collections&nbsp;containing similarly challenging material. &nbsp;As part of the project we will develop guidelines/methodology for curatorial care - and research&nbsp;access to -&nbsp;such material: an&nbsp;advisory committee&nbsp;of&nbsp;curators, academics, lawyers and regional medical humanities network representatives&nbsp;will support us and a case paper will be published at the end&nbsp;to serve as a model for other 'challenging' archives.</p> <p>&nbsp;</p> <p>FB&nbsp;is an artist whose extraordinary body-based performances have often involved blood-letting.&nbsp; His work, which explores the limits of the body, touching on pain, suffering and sexuality in contemporary culture, attracts considerable multi-disciplinary research&nbsp;interest, from art historians, artists and curators to medical humanities historians and anthropologists researching questions of the body as a site of connection between the social, bio-medical, political and affective forces that constitute contemporary life and well-being.</p>

Amount: £136,049
Funder: The Wellcome Trust
Recipient: University of Bristol

J W Ballantyne a Hidden Collection in the Royal College of Physicians of Edinburgh 16 Nov 2017

<p>The Royal College of Physicians of Edinburgh Sibbald Library is requesting funding to catalogue and conserve an important collection on developmental medicine built up by J W Ballantyne, a pioneering specialist in ante-natal care.</p> <p>The key goal is to enable wider research access to the collection through the creation of 3,325 MARC format catalogue records (supplemented by archive catalogue entries).</p> <p>&nbsp;</p>