- Total grants
- Total funders
- Total recipients
- Earliest award date
- 24 Aug 2004
- Latest award date
- 16 Jul 2018
- Total GBP grants
- Total GBP awarded
- Largest GBP award
- Smallest GBP award
- Total Non-GBP grants
An Analysis of Health Behaviour Modifications in Alleviating Fear of Cancer Recurrence (FCR) 01 Apr 2016
Cancer afflicts a considerable number of people and may have significant impact on them, such as heart problems and infertility. Distressful emotions, including loneliness and Fear of Cancer Recurrence (FCR) might be experienced. FCR is extrememly common among cancer survivors to varying degrees. In addition, high levels have been associated with depression, hopelessness and other undesirable consequences . As a highly prevalent unmet need of cancer survivors, such implications on their quality of life reveal the importance of research into FCR to improve care for cancer survivors. This research project aims to further investigate the relationship between loneliness, distress and FCR. In particular, it also seeks to study whether modifications in health behaviours can alleviate FCR. Research suggests that diet and physical activity may be key factors in reducing cancer risk. Furthermore, it is thought that FCR might motivate health behavior modifications in cancer survivors. However, more research is needed to delineate this relationship. Moreover, a theoretical understanding of if and how changing health behaviours may help the survivors manage their fears is not available. Therefore, the project will explore the relations between health behaviour modifications and FCR through interviews and surveys to attain both qualitative and quantitative data.
In this project, a novel Molecular Bacterial Load (MBL) assay that is able to quantify viable Pseudomonas in samples will be developed. Primers will specifically target the 16SrRNA in Pseudomonas bacteria. This will allow the assay to determine the presence of Pseudomonas bacteria in samples, as well as quantify the number of organisms that are alive. Compared to current techniques for determining the presence and viability of organisms in acute and chronic Pseudomonas infections, the MBL assay will provide results significantly faster, and will be much more specific. This means that the technology could be applied clinically as a new tool to monitor the response of patient to antimicrobial therapy, and ensure that there is not resistance to the selected treatment. This is relevant particularly in patients with chronic respiratory disease such as Cystic Fibrosis, where a chronic (and inadequately treated) Pseudomonas infection can significantly increase morbidity and risk of mortality. Key objectives for this project include: developing a 16SrRNA primer for Pseudomonas to be used in the MBL assay; to determine the specificity of the assay by testing it against organisms that are taxonomically related to Pseudomonas; and to validate the assay with a pre-existing clinical sample set.
Human stem cells bring a great promise for personalized regenerative medicine, in vitro studies of patient-specific human diseases and new generation of effective drug-screening methods. In the last years, patient-derived induced pluripotent stem cells (iPSC) have been increasingly used in clinical trials of novel therapies and more fundamental studies on the genetic neuronal disorders. However, the great variability and heterogeneous behaviour of patient-derived iPSC lines has been recognized as a major obstacle in their clinical applications and in conclusive interpretation of in vitro studies and drug screening assays. Their functional electrical properties responsible for the neural function are particularly important for the success of neuroregenerative stem cell treatment. However, they are extremely difficult to study using traditional electrode-based methods and the selection of functionally optimal transplant cell line is currently unfeasible. In this project, we will apply our recently developed experimental system capable of rapid functional analysis of living neural cells to human iPSC-derived neurons. Using our light-based optogenetics approach we will aim to demonstrate an efficient methodology for selection of the optimal transplant iPSC line for neuroregenerative therapy based on its electrophysiological characteristics. Our non-invasive approach will enable complete electrophysiological characterization of hundreds of cells within each sample.
Archival Research into the Theatrical Component of Early Modern Spanish Medical Practice. 29 May 2015
Archival research in four different locations in Spain, one week each. In each case, the goal is to find information in legal and other documents regarding any theatrical component in any medical practice, including the sale of medicine. These components can range from simple street-hawking, to setting up shop in a public place, to oration and speech-making in a public place, including song-and-dance as a means to attract and convince patients. 1) Archivo Hist rico Nacional: The Consejos section is housed here, which contains legal documents related to the licensing and disputes involving medical practitioners in Madrid. 2) Archivo General de Simancas: This archive contains legal documents related to the licensing and disputes involving medical practitioners, especially salary disputes, that are not contained in the Archivo Hist rico Nacional. 3) Archivo de la Real Chanciller a de Valladolid: This archive contains the documentation of many lawsuits involving medical pract itioners. 4) Archivo del Reino de Valencia: This archive a source of documentation on what Mar a Luz L pez Terrada calls extra-academic medical practices , evidence of which may not be covered by documents in other archives, or has been lost, or destroyed elsewhere.
Grant to Norfolk Knitters and Stitchers 20 Mar 2015
as a staff grant towards the running costs of an organisation which brings people together to knit and sew for good causes
The project is to set up craft/social clubs for older people. The money is for hire of meeting rooms, materials and travel costs for outings.
WW2 reminiscence project 24 Jun 2005
CSV Media Northern Ireland will use their award to hold events in order to collect memories about life during the Second World War. These memories will be recorded on the BBC People's War website. The memories will be recorded by trained volunteers along with Community Service Volunteer staff.
RSVP Volunteers 14 Dec 2005
Under their Retired and Senior Volunteer Programme, this group will place volunteers over 50 years of age with York's Out Of School clubs. They will bring experience and creativity to children under 10 years old. The award is for volunteer expenses, promotional materials, room hire and CSV travel expenses.
RSVP Devon 16 Apr 2009
This charity will use funding to hold a publicity drive to recruit and train new volunteers. The project will encourage more people to volunteer and will enable the charity to extend its service throughout Devon. The grant will contribute towards events costs, display stands, projector hire, publicity and training.