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Current Filters

Funders:
The Wellcome Trust
Currency:
GBP

Results

Biomedical Vacation Scholarship 25 Jun 2012

Not available

Amount: £1,441
Funder: The Wellcome Trust
Recipient: Maynooth University

Biomedical Vacation Scholarship 25 Jun 2012

Not available

Amount: £4,560
Funder: The Wellcome Trust
Recipient: Birkbeck University of London

Translational Medicine and Therapeutics Programme at the University of Cambridge: 'Activating Akt mutations and metabolism: translational and therapeutic opportunities.' 21 May 2012

To elucidate the mechanisms by which the AKT2-E17K mutation affects the regulation of the downstream substrates involved in glucose and lipid metabolism in vitro approaches including western blotting, immunoprecipitation, quantitative PCR and confocal microscopy will be used. Complementary studies with AKT inhibitors will be performed and their effects on the above outcomes will be assessed. Transgenic mouse models of the Akt2-E17K and Akt1-E17K mutations have been obtained and detailed phenotyping of these mice will provide in vivo insights into the consequences of the E17K mutation as well as reveal important insights into the isoform specific functions of these enzymes. In addition, these mice will be used for pre-clinical studies investigating the clinical efficacy of compounds that impact upon AKT signalling. Collectively, the data collected from these studies will inform future clinical studies investigating the efficacy of AKT inhibitors in disease states characterised by hyperinsulinism.

Amount: £144,918
Funder: The Wellcome Trust
Recipient: University of Cambridge

Interdisciplinary Training Programme for Clinicians in Translational Medicine and Therapeutics at the University of Cambridge: Support for the 2012 MPhil Appointments. 31 Aug 2012

We propose an innovative training scheme for Translational Medicine and Therapeutics (TMAT) which builds on the exceptional conjunction on the Cambridge campus of leading scientists and clinical specialists, with an industrial research environment embraced both by international pharmaceutical and local biotech companies. Much of this is found under the same roof, the Addenbrookes Centre for Clinical Investigation (ACCI), with a track record of integrated training: academic with industrial, clinical with scientific, pharmacology & therapeutics with patient-based specialties. The novel TMAT programme will attract the brightest candidates at several levels of seniority, ranging from MB PhD students to clinical lecturers, some wishing translational skills in their chosen specialty, others not yet differentiated who may become future leaders and teachers of TMAT. Each trainee will have a customised programme. Part of this will be a bespoke, modular MSc modelled on the well-known small-group lectures and supervisions of the Cambridge final year undergraduate courses. However the centrepiece for most candidates will be a PhD including formal teaching in a wide range of translational and pharmacological skills, and a project which takes proof-of-concept studies in cell or animal systems forward to proof-of-concept studies in humans. We have assembled an outstanding faculty of PhD supervisors spanning a wide choice of skills and experience in basic and clinical science. All trainees will have the opportunity for hands-on exposure to the design and conduct of experimental medicine studies investigating the therapeutic potential of new drugs, in collaboration with our industrial partner, GlaxoSmithKline (GSK). Our product will be a new generation of clinician scientists with 360-degree vision of the complex landscape of modern therapeutic medicine, who can rise to the challenges and opportunities of 21st century drug development.

Amount: £18,531
Funder: The Wellcome Trust
Recipient: University of Cambridge

Biomedical Vacation Scholarship 25 Jun 2012

Not available

Amount: £4,320
Funder: The Wellcome Trust
Recipient: Aston University

Biomedical Vacation Scholarships 25 Jun 2012

Not available

Amount: £4,140
Funder: The Wellcome Trust
Recipient: Anglia Ruskin University

Biomedical Vacation Scholarship 25 Jun 2012

Not available

Amount: £25,460
Funder: The Wellcome Trust
Recipient: King's College London

Biomedical Vacation Scholarship 25 Jun 2012

Not available

Amount: £3,780
Funder: The Wellcome Trust
Recipient: Keele University

Biomedical Vacation Scholarship 25 Jun 2012

Not available

Amount: £1,440
Funder: The Wellcome Trust
Recipient: Quadram Institute Bioscience

Biomedical Vacation Scholarship. 25 Jun 2012

Not available

Amount: £1,440
Funder: The Wellcome Trust
Recipient: University of Portsmouth

Biomedical Vacation Scholarship 25 Jun 2012

Not available

Amount: £1,440
Funder: The Wellcome Trust
Recipient: University of Durham

Biomedical Vacation Scholarship 25 Jun 2012

Not available

Amount: £5,760
Funder: The Wellcome Trust
Recipient: University of Dundee

Biomedical Vacation Scholarship. 25 Jun 2012

Not available

Amount: £4,320
Funder: The Wellcome Trust
Recipient: University of Southampton

Biomedical Vacation Scholarship. 25 Jun 2012

Not available

Amount: £3,040
Funder: The Wellcome Trust
Recipient: Roehampton University

Biomedical Vacation Scholarship. 25 Jun 2012

Not available

Amount: £5,760
Funder: The Wellcome Trust
Recipient: University of Reading

Biomedical Vacation Scholarship. 25 Jun 2012

Not available

Amount: £12,969
Funder: The Wellcome Trust
Recipient: National University of Ireland Galway

Biomedicl Vacation Scholarship 25 Jun 2012

Not available

Amount: £20,160
Funder: The Wellcome Trust
Recipient: University of Cambridge

Biomedical Vacation Scholarship. 25 Jun 2012

Not available

Amount: £10,080
Funder: The Wellcome Trust
Recipient: University of Bristol

Biomedical Vacation Scholarship. 25 Jun 2012

Not available

Amount: £1,440
Funder: The Wellcome Trust
Recipient: Teesside University

Biomedical Vacation Scholarship. 25 Jun 2012

Not available

Amount: £5,700
Funder: The Wellcome Trust
Recipient: St George's University of London