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The National Lottery Community Fund (226,066) Co-operative Group (16,503) The Wellcome Trust (16,377) Sport England (15,905) The National Lottery Heritage Fund (10,201) Garfield Weston Foundation (5,922) Lloyds Bank Foundation for England and Wales (5,467) The Henry Smith Charity (4,590) Northern Rock Foundation (4,331) Community Foundation serving Tyne & Wear and Northumberland (4,320) Esmée Fairbairn Foundation (4,213) BBC Children in Need (4,183) Woodward Charitable Trust (2,767) Quartet Community Foundation (2,683) Department for Transport (2,577) The Tudor Trust (2,554) Paul Hamlyn Foundation (2,367) Wolfson Foundation (2,210) Essex Community Foundation (1,876) Greater London Authority (1,846) City Bridge Trust (1,778) Community Foundation for Surrey (1,776) County Durham Community Foundation (1,659) Heart Of England Community Foundation (1,635) The Robertson Trust (1,542) Suffolk Community Foundation (1,428) Comic Relief (1,411) Glasgow City Council (1,365) The Clothworkers Foundation (1,358) London Borough of Southwark (1,260) Somerset Community Foundation (1,259) Nesta (1,247) Guy's and St Thomas' Charity (1,230) Corra Foundation (1,184) London Catalyst (1,174) Oxfordshire Community Foundation (1,139) Birmingham City Council (1,103) CAF (1,004) Leeds Community Foundation (905) Masonic Charitable Foundation (895) Power to Change Trust (870) Sussex Community Foundation (835) Two Ridings Community Foundation (792) Trafford Housing Trust Social Investment (779) Ministry of Justice (774) National Churches Trust (760) Walcot Foundation (755) Devon Community Foundation (715) The Dulverton Trust (680) A B Charitable Trust (665) See Less

Results

The Wellcome Centre for Molecular Parasitology 20 Sep 2006

The Wellcome Centre for Molecular Parasitology The Centre originated in 1987, when Anty Tait and Dave Barry were funded by the Wellcome Trust to set up the Wellcome Unit of Molecular Parasitology, to apply molecular, genetic and biochemical technologies to the investigation of basic questions in the biology of parasites. The Unit had some core funding and was based in the Dept Veterinary Parasitology (Tait) and the Institute of Genetics (Barry), on separate campuses of the University of Glasgow. In 1994, via a grant for the Wellcome Trust, the Unit was amalgamated in new laboratories in the Anderson College. At the quinquennial review in 1998, the Unit applied successfully for Wellcome Trust Centre status. In June 2005, the Centre will move to the new Glasgow Biomedical Research Centre (JIIF/SRIF funded), along with immunobiologists and structural biologists. The Centre is a hub of parasitologists using a wide range of modern approaches to understanding aspects of the organismal biology of parasites. Its missions are: Form a centre of excellence for the molecular and genetic study of parasites Provide and sustain a modern laboratory environment Provide quality research training for science and veterinary graduates. The Centre has 8 research groups (and Acosta-Serrano from Sept 2003), studying mainly 5 parasite genera and the free-living nematode C. elegans, an excellent model for parasitic nematodes, which are diffi8uclt to study. Its research programmes are integrated into three of these themes. The first is the generation of diversity, which is core to the success of parasites. The second, which overlaps with the first, is the control and synthesis of surface molecules, many of which are key to host-parasite interaction. The third is differentiation through the life and cell cycle, steps essential for colonisation of, and transmission between, hosts. Due to the several levels of discussion within the Centre, there is much exchange of ideas within each theme and several of the groups have major collaborations, through to publication level.

Amount: £319,481
Funder: The Wellcome Trust
Recipient: University of Glasgow

Identification and functional analysis of susceptibility genes in multifactoral disease: Award for Years 4 and 5. 20 Sep 2006

The Wellcome Trust Centre for Human Genetics was established in 1994 to undertake research into the genetic basis of common diseases. The scientific objective of the Centre is to gain insight into mechanisms controlling geneticsusceptibility to human disease including the localization and identification of disease genes, functional characterization of gene variants responsible forsusceptibility, understanding how gene variants contribute to risk of disease in the population and how genetic factors contribute biologically to a diseaseprocess. In order to achieve this scientific objective the Centre's strategy was to bring together multidisciplinary research groups collaborating on humanand rodent genetics, genetic epidemiology, functional analysis of disease genes, cell and developmental biology and structural biology. In addition, theCentre has a strong focus of expertise, equipment and resources centralized inCore groups allowing all research groups to benefit and expand their research strategies. The Core groups in Genomics, Molecular Cytogenetics and Microscopy, Bioinformatics and Statistical Genetics, and Transgenics provide first-rate services and perform research and development on new platform technologies as well as algorithms and databases needed to analyse complex datasets. This application is to continue our Centre status and provide funding for the running of these Core groups over the next five years.

Amount: £4,184,432
Funder: The Wellcome Trust
Recipient: University of Oxford

Core support for Wellcome Trust/Cancer Research UK Gurdon Instiute. Award for years 4 and 5. 20 Sep 2006

This application requests the continuation of core support to the Wellcome Trust/Cancer Research UK Gurdon Institute. The aim of the Institute, an integrated part of Cambridge University, is to contribute to an understanding of normal animal development, including the processes of cell differentiation, morphogenesis and cell proliferation, and to explain how, should these processes fail, cancers may arise. The Institute attempts to achieve these objectives by recruiting the best scientists and by ensuring that they have the best possible environment for their work. Recruitment is carried out by a committee of Group Leaders, with the main criterion for appointment being scientific excellence. This application is concerned with providing the best scientific environment for our researchers, and indeed the Institute's core support is one of its most important assets, allowing our scientists to spend as much time as possible on their work. This support provides practical assistance, such as media preparation, and secretarial and administrative assistance, including help with grant applications and equipment procurement. It also provides computer staff and a bioinformatician, as well as expertise in confocal microscopy. Core support is essential if the Institute is to maintain its position as a leading centre of cell, molecular and developmental biology.

Amount: £3,005,149
Funder: The Wellcome Trust
Recipient: University of Cambridge

Renewal of core support for the Wellcome Trust Centre for Cell-Matrix Research. 20 Sep 2006

The Wellcome Trust Centre for Cell-Matrix Research (WTCCMR) is a multidisciplinary research centre embedded within the Faculty of Life Sciencesat the University of Manchester. The long-term aims of the WTCCMR are to elucidate the structure and function of extracellular matrices (ECM) and theircellular receptors, to define the role of ECM and cell-ECM interactions in normal development and human diseases, and to develop approaches for preventing and treating such diseases. The strategy employed has been to recruit a team of researchers with overlapping interests and complementary skills, and to facilitate their work by providing a physical and technologicalenvironment of the highest standard. Over the next five years, research within the WTCCMR will be packaged into four interlinked programmes - (1) molecular basis and cellular control of ECM assembly, (2) organisation of signalling at the cell-ECM interface, (3) microenvironmental determination of cell fate, and (4) cell-ECM engineering and tissue regeneration. This research plan has been crafted to advance our understanding of the basic mechanisms of ECM function, and to suggest experimental strategies for correcting ECM defects and repairing dysfunctional tissues. This application seeks to renew Centre status and requests funds to support the core infrastructure of the WTCCMR.

Amount: £929,747
Funder: The Wellcome Trust
Recipient: University of Manchester

Core support for Wellcome Trust Centre for Cell Biology. 20 Sep 2006

The broad aim of the Wellcome Trust Centre is to create a world-class research grouping that is at the forefront of research on fundamental aspects of cell biology. Since the creation of the Centre four years ago, we have made significant progress towards this aspiration. We appointed a core of professorial level scientists who are leaders in their fields plus more junior group leaders who have acquired fellowships in open competition. Our most important assets are the individual scientists who direct and manage their independently funded research groups and whose ability largely determines our research output. The Centre's specific goal is to make discoveries that take the understanding of cells to new levels. We believe that creative research of this kind flourishes where interaction, scientific rigour and constructive criticism are pervasive. The core funding associated with being a Centre allows us to realise these ideals. We have promoted a culture of scientific excellence through communal scientific activites that reinforce our ethos (seminars, retreats, Fellows Meetings, etc) and through sharing of state-of-theart core resources, equipment and facilities. In future, we intend to strengthen our scientific profile in several ways. 1. We will continue to seek cell biologists of excellence for our faculty. 2. We will improve the Centre's instumentation stock in order to maintain our status at the cutting edge in a time of feverish technological development. 3. We will develop our "outreach" activities in order to more effectively communicate the excitement of our research to the public. 4. We will enhance our mentoring of scientists at all levels. 5. We will seek to institute a PhD programme that will allow us to stimulate and educate a new generation of scientists.

Amount: £1,539,302
Funder: The Wellcome Trust
Recipient: University of Edinburgh

Core support for Wellcome Trust Centre for Cell Biology. 22 May 2006

The broad aim of the Wellcome Trust Centre is to create a world-class research grouping that is at the forefront of research on fundamental aspects of cell biology. Since the creation of the Centre four years ago, we have made significant progress towards this aspiration. We appointed a core of professorial level scientists who are leaders in their fields plus more junior group leaders who have acquired fellowships in open competition. Our most important assets are the individual scientists who direct and manage their independently funded research groups and whose ability largely determines our research output. The Centre's specific goal is to make discoveries that take the understanding of cells to new levels. We believe that creative research of this kind flourishes where interaction, scientific rigour and constructive criticism are pervasive. The core funding associated with being a Centre allows us to realise these ideals. We have promoted a culture of scientific excellence through communal scientific activites that reinforce our ethos (seminars, retreats, Fellows Meetings, etc) and through sharing of state-of-theart core resources, equipment and facilities. In future, we intend to strengthen our scientific profile in several ways. 1. We will continue to seek cell biologists of excellence for our faculty. 2. We will improve the Centre's instumentation stock in order to maintain our status at the cutting edge in a time of feverish technological development. 3. We will develop our "outreach" activities in order to more effectively communicate the excitement of our research to the public. 4. We will enhance our mentoring of scientists at all levels. 5. We will seek to institute a PhD programme that will allow us to stimulate and educate a new generation of scientists.

Amount: £1,726,327
Funder: The Wellcome Trust
Recipient: University of Edinburgh

WELLCOME TRUST CENTRE FOR STEM CELL RESEARCH 20 Sep 2006

The new Institute for Stem Cell Biology in Cambridge will be an international centre of excellence in fundamental stem cell research. The Institute will focus on definition of the genetic and biochemical mechanisms that control stem cell fate, providing foundations for applications in disease modelling, drug discovery and regenerative medicine. This proposal is for provision of core resources for embryonic stem cell manipulation and transgenesis. A central resource of skilled personnel will maximise research productivity and continuity, promote cooperation and synergy, and accelerate technological innovation. Timely and efficient production of customised gene-modified stem cells and mice is essential underpinning. Specialised expertise will support advanced genetic engineering of mouse and human stem cells, and operation of robotic platforms to develop screening methodologies for isolating genetic, protein and chemical regulators. A dedicated PdD programme in stem cell biology will capitalise on the opportunity for high level research training provided by the intellectual environment and core facilities in the Institute. A Strategic Award will immediately establish the Institute for Stem Cell Biology amongst the best-resourced and most attractive environments for stem cell research world-wide, providing a magnet for recruitment, and a much-needed focus for UK and European stem cell biology.

Amount: £6,956,531
Funder: The Wellcome Trust
Recipient: University of Cambridge

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £200,000
Funder: The Wellcome Trust
Recipient: University of Liverpool

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £200,000
Funder: The Wellcome Trust
Recipient: University of Leeds

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £150,000
Funder: The Wellcome Trust
Recipient: University of Warwick

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £200,000
Funder: The Wellcome Trust
Recipient: University of Leicester

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £300,000
Funder: The Wellcome Trust
Recipient: Imperial College London

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £200,000
Funder: The Wellcome Trust
Recipient: University of Sheffield

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £150,000
Funder: The Wellcome Trust
Recipient: University of St Andrews

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £300,000
Funder: The Wellcome Trust
Recipient: University of Edinburgh

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £200,000
Funder: The Wellcome Trust
Recipient: University of Nottingham

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £200,000
Funder: The Wellcome Trust
Recipient: University of Birmingham

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £150,000
Funder: The Wellcome Trust
Recipient: Royal Veterinary College

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £150,000
Funder: The Wellcome Trust
Recipient: University of York

VALUE IN PEOPLE AWARD. 30 Aug 2006

Not available

Amount: £150,000
Funder: The Wellcome Trust
Recipient: University of Durham