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Search results (Displaying 797 grants)

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Earliest award date
17 Oct 2005
Latest award date
30 Sep 2020
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From vision to action: Systems analysis of sensorimotor circuitry controlling visually-guided behaviour
<p style="margin-left: 0cm; margin-right: 0cm">Despite the emergence of technologies to record from thousands of neurons during animal behaviour, two major issues are currently limiting the transfer and utilisation of ultra-high-dimensional datasets between neuroscience groups. First, raw data files are often enormous, making data transfer inconvenient and expensive. Second, there is no common fo… more
Amount: £48,349
Global Health 50/50: Towards accountability for gender equality in global health
<p>We propose to establish <em>Global Health 50/50</em>, a new initiative seeking to advance action and accountability for gender-equality in global health.&nbsp;</p> <p>Gender is a key driver of power to exercise the right to health, including exposure to risks of poor health, health seeking behaviours, and access to quality health care. Gender inequalities continue to define and drive career p… more
Amount: £29,764
Amount: £50,000
A Hotbed for Liver Cancer: Biomedicine, Exposure and Uncertainty in West Africa
<p>Incidence rates of primary liver cancer vary strikingly across the globe. West Africans are more likely than most populations to develop and die from it. Focusing on Senegal and The Gambia, my project investigates how this association between place and <em>intensity of susceptibility</em> to liver cancer has been understood, and how it has been maintained by gaps in protection from risky expos… more
Amount: £301,612
Developing novel gene therapy technology for treatment of glycine encephalopathy
"Glycine encephalopathy, also known as non-ketotic hyperglycinaemia (NKH), is a life limiting inherited neuro-metabolic disease which presents soon after birth and leads to severe neurological outcomes including epilepsy and profound developmental delay. Current treatments for NKH are neither effective long-term, nor curative. Glycine encephalopathy is characterized by accumulation of glycine and… more
Amount: £365,837
Jeevan Shakti Mela - Funfair for lifeforce
<p>Type 2 Diabetes mellitus (T2DM) is often not well understood among marginalized populations, but its prevalence is increasing, particularly in low-income countries. We will address this challenge in rural plains Nepal, enabling female Maithil artists from the Janakpur Women&rsquo;s Development Centre (JWDC) to engage with communities about T2DM through research, drama, and a funfair. First, a … more
Amount: £75,000
Skeletal muscle channelopathies: severe infantile phenotypes and sudden infant death syndrome
<p>Skeletal muscle channelopathies are mainly autosomal dominant disorders that typically cause muscle symptoms of myotonia, periodic paralysis or progressive myopathy. Until now the muscle channelopathy phenotypes described are disabling but not fatal. Pilot data implicates ion channel dysfunction in severe infantile phenotypes with respiratory compromise and some cases of sudden infant death sy… more
Amount: £283,711
Wellcome Centre for Human Neuroimaging
<p>The Research Enrichment fund will enable us to embed public engagement (PE) into our Wellcome Centre research process.&nbsp;If funded, we will have achieved the following at the end of the proposed Research Enrichment programme:</p> <p>(1) &nbsp;Established a cultural change within our Centre where PE is integrated into all of our research programmes, with more researchers doing PE than not.&… more
Amount: £266,960
Gender, health and the afterlife of colonialism. Engaging new problematisations to improve maternal and infant survival.
<p style="margin-left: 0cm; margin-right: 0cm">I will work at the intersection of public health, decolonisation theory and feminist ethnography to generate evidence and promote gender responsive strategies aimed at improving maternal and infant survival.</p> <p style="margin-left: 0cm; margin-right: 0cm">Historical gender and ethnic inequalities underlie low rates of skilled birth attendance and… more
Amount: £446,111
Auditory structured sequence learning on multiple timescales
<p>Regularities play an important role in analysing auditory scenes; for example, by exploiting the predictable sounds of the car engine, a driver can effortlessly ignore this irrelevant noise, freeing cognitive resources to focus on the road. Regularities also play an important role in language, dictating the relationship between syllables in word or the order words in a sentence, and have been … more
Amount: £300,000
Neurobiological foundations of flexible social behaviour
<p>A core aspect of healthy social function is the ability to map our private beliefs onto those that we express publicly according to the social context. It may be socially appropriate to express gratitude for a gift we do not want, or remorse for an action we do not regret. My goal is to understand the neurocognitive mechanisms supporting context-appropriate social behaviours and how they are a… more
Amount: £300,000
Skeletal muscle channelopathies: severe infantile phenotypes and sudden infant death syndrome
<p>We will have achieved a comprehensive understanding of not only the most appropriate ways and times to discuss inclusion in a SUDIC registry with bereaved families but how we can better inform and support them through the death of their child and the multi-disciplinary investigation that follows a sudden death. We will have established:</p> <ul> <li>What families understand now about the pro… more
Amount: £16,000
Our Planet, Our Health award: Complex Urban Systems for Sustainability and Health
<p style="margin-left: 0cm; margin-right: 0cm">Three work streams will address participatory local action (outcomes 1-3), national media (outcome 4), and global communication (outcome 5). After two years, we will have stimulated local discussion and co-designed and implemented public engagement interventions for urban environmental sustainability and health &ndash; centred on waste management - w… more
Amount: £248,615
Vacation Scholarships 2017 - University College London
<p>Vacation Scholarships 2017 - University College London</p>
Amount: £25,500
Genetic background effects in human iPSCs and iPSC-derived cell types
<p>Human induced pluripotent stem cells (iPSC) have emerged as a key model system to study the function of genetic variants, as they provide access to relevant cell types and developmental lineages through cellular differentiation. However, while it has been shown that the genetic background of the donor individual has an effect on molecular phenotypes measured from iPSCs, it is currently not kno… more
Amount: £99,935
Investigation of protein CoAlation in the process of apoptosis
<p>CoAlation is a novel post-translational modification to proteins whereby Coenzyme A is covalently attached to proteins. It occurs as part of the oxidative stress response as an alternative mechanism to protein glutathionylation. It is specifically a modification of enzymes involved in cellular metabolism and protects catalytic thiol groups on active site cysteine residues from irreversible dam… more
Amount: £0