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Search results (Displaying 613 grants)

Total grants
613
Total funders
1
Total recipients
1
Earliest award date
17 Oct 2005
Latest award date
30 Sep 2020
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A Hotbed for Liver Cancer: Biomedicine, Exposure and Uncertainty in West Africa
<p>Incidence rates of primary liver cancer vary strikingly across the globe. West Africans are more likely than most populations to develop and die from it. Focusing on Senegal and The Gambia, my project investigates how this association between place and <em>intensity of susceptibility</em> to liver cancer has been understood, and how it has been maintained by gaps in protection from risky expos… more
Amount: £301,612
Developing novel gene therapy technology for treatment of glycine encephalopathy
"Glycine encephalopathy, also known as non-ketotic hyperglycinaemia (NKH), is a life limiting inherited neuro-metabolic disease which presents soon after birth and leads to severe neurological outcomes including epilepsy and profound developmental delay. Current treatments for NKH are neither effective long-term, nor curative. Glycine encephalopathy is characterized by accumulation of glycine and… more
Amount: £365,837
Skeletal muscle channelopathies: severe infantile phenotypes and sudden infant death syndrome
<p>Skeletal muscle channelopathies are mainly autosomal dominant disorders that typically cause muscle symptoms of myotonia, periodic paralysis or progressive myopathy. Until now the muscle channelopathy phenotypes described are disabling but not fatal. Pilot data implicates ion channel dysfunction in severe infantile phenotypes with respiratory compromise and some cases of sudden infant death sy… more
Amount: £283,711
Wellcome Centre for Human Neuroimaging
<p>The Research Enrichment fund will enable us to embed public engagement (PE) into our Wellcome Centre research process.&nbsp;If funded, we will have achieved the following at the end of the proposed Research Enrichment programme:</p> <p>(1) &nbsp;Established a cultural change within our Centre where PE is integrated into all of our research programmes, with more researchers doing PE than not.&… more
Amount: £266,960
Gender, health and the afterlife of colonialism. Engaging new problematisations to improve maternal and infant survival.
<p style="margin-left: 0cm; margin-right: 0cm">I will work at the intersection of public health, decolonisation theory and feminist ethnography to generate evidence and promote gender responsive strategies aimed at improving maternal and infant survival.</p> <p style="margin-left: 0cm; margin-right: 0cm">Historical gender and ethnic inequalities underlie low rates of skilled birth attendance and… more
Amount: £446,111
Auditory structured sequence learning on multiple timescales
<p>Regularities play an important role in analysing auditory scenes; for example, by exploiting the predictable sounds of the car engine, a driver can effortlessly ignore this irrelevant noise, freeing cognitive resources to focus on the road. Regularities also play an important role in language, dictating the relationship between syllables in word or the order words in a sentence, and have been … more
Amount: £300,000
Neurobiological foundations of flexible social behaviour
<p>A core aspect of healthy social function is the ability to map our private beliefs onto those that we express publicly according to the social context. It may be socially appropriate to express gratitude for a gift we do not want, or remorse for an action we do not regret. My goal is to understand the neurocognitive mechanisms supporting context-appropriate social behaviours and how they are a… more
Amount: £300,000
Our Planet, Our Health award: Complex Urban Systems for Sustainability and Health
<p style="margin-left: 0cm; margin-right: 0cm">Three work streams will address participatory local action (outcomes 1-3), national media (outcome 4), and global communication (outcome 5). After two years, we will have stimulated local discussion and co-designed and implemented public engagement interventions for urban environmental sustainability and health &ndash; centred on waste management - w… more
Amount: £248,615
Overcoming constraints on T cells in the HBV-infected liver
<p>My request for enhancement funding arises from the component of my existing award focused on developing T cell immunotherapy of hepatitis B and hepatocellular carcinoma using patient samples. We recently made important contributions to the testing of genetically redirected T cells for a first-in-man treatment of HBV-related hepatocellular carcinoma1. We are also collaborating with academic and… more
Amount: £175,008
Advancing Psychiatric Mapping Translated into Innovations for Care: PsyMaptic-A
<p>My current and previous Wellcome Trust Fellowships (Henry Wellcome, 2009-13; Henry Dale 2014- present) focus on important aetiological questions about psychotic disorders, using epidemiological data. Psychotic disorders are a debilitating set of mental health disorders, characterised by hallucinations, delusions and cognitive deficits. My research demonstrates that these disorders have a robus… more
Amount: £204,479
University College London/Birkbeck Interdisciplinary Programme in Structural, Computational and Chemical Biology
<p>University College London/Birkbeck Interdisciplinary Programme in Structural, Computational and Chemical Biology</p>
Amount: £133,252
Neuroscience
Not available
Amount: £133,252
UCL - Neuroscience
Not available
Amount: £133,252
UCL - Neuroscience
Not available
Amount: £133,252
University College London/Birkbeck Interdisciplinary Programme in Structural, Computational and Chemical Biology
<p>University College London/Birkbeck Interdisciplinary Programme in Structural, Computational and Chemical Biology</p>
Amount: £133,252
UCL - Neuroscience
Not available
Amount: £133,252
Harnessing Diversity Generating Retroelements (DGRs) for in vivo evolution
<p>The goal of the project is to express the reverse transcriptase (RT), central to the Bordertella phage BPP-1 diversity generating retroelement (DGR), and test it for synthetic nucleic acid (XNA) synthesis as well as reverse transcription. In addition, I will focus on cloning the BPP-1 DGR elements into E. coli, creating a circuit where DGR function can activate a selectable marker (e.g. kanR).… more
Amount: £2,000
Patient and public involvement in priority setting: should we listen to the will of the people?
<p>Decision-makers tasked with allocating resources within health systems often face huge pressure about funding decisions from patients and the public, often described as lobbying. One question that we may want to settle is how far particular priority setting decisions <em>are</em> influenced by lobbying and lobbyists. However, we might also ask another, ethical question: namely, to what extent … more
Amount: £149,624