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Your search ‘’ returned 109 results in ‘All grant fields’

Search results (Displaying 109 grants)

Total grants
109
Total funders
1
Total recipients
1
Earliest award date
17 Jan 2014
Latest award date
30 Dec 2017
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Vacation Scholarships 2017 - University of Cambridge
<p>Vacation Scholarships 2017 - University of Cambridge</p>
Amount: £21,500
The role of metabolic enzymes in the nucleus
Cells exposed to oxidants re-route their main carbon flow from glycolysis to the pentose phosphate pathway (PPP), by two different mechanisms. One bases on a biochemical block and operates purely on a metabolic level, the other on transcriptional regulation. We found that the two processes compartmentalize over time: After contact with the stressor, the cell induces the metabolic transition in se… more
Amount: £45,000
Seminal Work: Sperm Science, Sterility, and Masculinity.
Male reproduction provides a rich site for exploring a variety of sociological themes and pressing social issues, including gender, sexuality, sexual orientation, global inequality, eugenics, ethics, epigenetics, environmental degradation, reproductive tourism, state-building, veteran rehabilitation, HIV stigma, and alternative family building. All of these themes will be explored at the upcoming… more
Amount: £4,200
Amount: £17,500
Virtual Fly Brain: a global informatics hub for Drosophila neurobiology
Drosophila allows unprecedented genetic dissection of a relatively small nervous system that supports complex behaviours. Exploiting this opportunity requires intuitive tools to help users query the expanding knowledge from the literature and bulk image data, in order to generate hypotheses about neural circuits, and find reagents that target the neurons concerned. Virtual Fly Brain (VFB) is the … more
Amount: £141,493
Medicine in medieval Egypt: creating online access to the medical corpus of the Cairo Genizah.
The Cairo Genizah Collection at Cambridge University Library is the single largest and most important collection of medieval Jewish manuscripts in the world. Comprising approximately 200,000 leaves, the discovery of this treasuretrove 100 years ago revolutionised the study of medieval Judaism and our understanding of the broader economic, social and intellectual history of the Mediterranean world… more
Amount: £95,089
Public Engagement Provision
<table> <tbody> <tr> <td>The&nbsp;Cairo Genizah Collection at Cambridge University Library is the single largest and most important collection of medieval Jewish manuscripts in the &nbsp; world. Comprising approximately 200,000 leaves, the discovery of this &nbsp; treasuretrove 100 years ago revolutionised the study of medieval Judaism and &nbsp; our understanding of the broader economic, social … more
Amount: £4,984
Does enhanced PI3K signalling render APDS patients susceptible to infections by interfering with B cell development and activation?.
Aberrant B cell activity can initiate or aggravate both immunodeficiencies and autoimmunity, and lead to lymphoproliferative disorders. PI3delta (phosphoinositide 3-kinase) is key in the signaling pathways regulating many immune cells, including B and T cells. We have identified patients with a dominant mutation in PI3delta (phosphoinositide 3-kinase ) catalytic subunit, a novel primary antibod… more
Amount: £363,305
Amount: £14,500
Hormone release from the gastrointestinal tract: mechanisms underlying bile acid-induced GLP-1 release and characterisation of somatostatin signalling.
<table> <tbody> <tr> <td>Gut hormones are key to the regulation of nutrient homeostasis and therefore particularly relevant to type-2 diabetes. This proposal involves determining&nbsp;the mechanisms underlying secretion of two gut hormones, glucagon-like peptide1 (GLP-1) and somatostatin (SST). GLP-1 is an incretin hormone&nbsp;released in response to components in the intestinal lumen and acts t… more
Amount: £18,565
Investigating the role of the bone morphogenetic proteins in the development of atherosclerosis.
<table> <tbody> <tr> <td>Atherosclerosis,&nbsp;a major cause of cardiovascular disease, affects millions of people every year. Atherosclerosis is characterised by vascular inflammation, lipi&nbsp; deposition and calcification in arterial walls. Evidence has shown that bone&nbsp;&nbsp;morphogenetic proteins (BMPs) are involved in thedevelopment of atherosclerosis. For example enhanced BMP2 activit… more
Amount: £44,568
Analysis of the Leucine Rich Repeat domain of Leucine Rich Repeat Kinase 2 andthe role of TLR4 mediated innate immune signalling in Parkinson's Disease
<table> <tbody> <tr> <td>Parkinson's Disease is a chronic neurodegenerative disease characterised by destruction&nbsp;of dopaminergic neurones within the substantia nigra pars compacta region of &nbsp; the midbrain. This project aims to elucidate molecular mechanisms underlying &nbsp; Parkinson's pathology. One avenue of research involves expression,&nbsp;purification and analysis of the leucine … more
Amount: £15,350
Selection activation of Pattern Recognition Receptors to enhance host protective immunity against infection
<table> <tbody> <tr> <td>The&nbsp;emergence of antibiotic resistance, coupled with the lack of an efficient &nbsp; vaccine means Salmonella infections are still a huge problem the developing &nbsp; world; development of a suitable vaccine would be a significant contribution &nbsp; to disease control. This project aims to identify a modified strain of &nbsp; Salmonella enterica serovar Typhimurium… more
Amount: £24,943
Public Engagement Provision.
<p>This proposal is to facilitate creation of a world-leading centre for fundamental and translational stem cell research. The Cambridge Stem Cell Institute (SCI) will build upon previous Wellcome Trust and Medical Research Council funding by drawing together 30 research teams into a cohesive centre. These groups will ultimately be co-located in a purpose-designed 8000m2 facility to be constructe… more
Amount: £171,011
Cambridge Stem Cell Institute Four year PhD studentships - Stem Cell Biology - Juergen Fink
<p>This proposal is to facilitate creation of a world-leading centre for fundamental and translational stem cell research. The Cambridge Stem Cell Institute (SCI) will build upon previous Wellcome Trust and Medical Research Council funding by drawing together 30 research teams into a cohesive centre. These groups will ultimately be co-located in a purpose-designed 8000m2 facility to be constructe… more
Amount: £60,540
Cambridge Stem Cell Institute Four year PhD studentships - Stem Cell Biology - Moritz Matthey
<p>This proposal is to facilitate creation of a world-leading centre for fundamental and translational stem cell research. The Cambridge Stem Cell Institute (SCI) will build upon previous Wellcome Trust and Medical Research Council funding by drawing together 30 research teams into a cohesive centre. These groups will ultimately be co-located in a purpose-designed 8000m2 facility to be constructe… more
Amount: £51,654
Cambridge Stem Cell Institute Four year PhD studentships - Stem Cell Biology - Elena Itskovich
<p>This proposal is to facilitate creation of a world-leading centre for fundamental and translational stem cell research. The Cambridge Stem Cell Institute (SCI) will build upon previous Wellcome Trust and Medical Research Council funding by drawing together 30 research teams into a cohesive centre. These groups will ultimately be co-located in a purpose-designed 8000m2 facility to be constructe… more
Amount: £35,897
Making scientific capacity in Africa: An interdisciplinary conversation (Application for co-funding with CRASSH, Cambridge).
The applicant and collaborator, together with a faculty research group at Cambridge, have successfully applied for an interdisciplinary conference at the university's Centre for Research in the Arts Social Sciences and Humanities (CRASSH), on the 'Making of scientific capacity in Africa', to be held in Cambridge in June 2014 (13th-14th). This Conference is linked to the Faculty Research Group 'Ci… more
Amount: £4,640