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Search results (Displaying 31 grants)

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Earliest award date
07 Feb 2019
Latest award date
19 Nov 2019
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Human sensitivity to short-wavelength light in non-image-forming vision: Toward a mechanistic understanding of the impact of blue light on sleep and circadian rhythms
<p>In chronobiology and sleep research, a significant proportion of past research studies examining the effects of light on the acute suppression of melatonin and on circadian photoentrainment have exclusively examined male participants, or naturally cycling female participants. The basis for this bias in participant recruitment is empirical evidence that the production of melatonin may be modula… more
Amount: £20,000
Function of novel human T cell subsets in host defence
<p>We are organising an international meeting on unconventional T cells (CD1-MR1: beyond MHC restricted lymphocytes). This is the major meeting for groups investigating these important components of immunity and occurs every 2 years, lasting 4 days. The aim of this proposal is to help support initiatives within this meeting to enhance diversity and inclusion. These include: Bursaries for those wi… more
Amount: £19,000
Mesh Community Engagement Network
<p>Mesh Community Engagement Network (<u>www.mesh-ce.org</u>) is a collaborative open-access webspace and networking project for people involved in community&nbsp;engagement with global health research (CE). Building on a successful pilot, we propose a new three-year strategic approach with a&nbsp;focus on measuring impact, using a <em>Theory of Change</em>&nbsp;to provide clarity on how we expec… more
Amount: £243,993
Amount: £12,456
Global Environmental (in)Activism: a Multi-sited Ethnography of Industrial Pollution, Illness and Community Resistance in Italy and Taiwan
<p>The research proposed is a multi-sited ethnographic investigation into the relationship between industrial pollution as a health threat and the ongoing social, political, and moral struggle of two communities living in close proximity to polluting sites. Through a comparative study of the people of Taranto, Italy, and Tainan, Taiwan, this project seeks to explore the political dimensions of en… more
Amount: £141,231
Material classification by man and machine: Understanding human perception using psychophysics and convolutional neural networks
The primary focus is to uncover computational mechanisms underlying material perception, with particular emphasis on "perceptual constancy" – the stability of judgements about objects in the world, despite changes in the proximal stimulus. My approach to this problem is to capitalise on recently developed deep-learning paradigms by evaluating and interpreting activation maps of convolutional neur… more
Amount: £300,000
Human sensitivity to short-wavelength light in non-image-forming vision: Toward a mechanistic understanding of the impact of blue light on sleep and circadian rhythms
Measurement and characterisation of light — whether it is in everyday contexts or in experimental and research settings — is notoriously non-trivial. Part of this is due to the complexity of the underlying concepts (e.g. measurement geometry, propagation of light in space). The goal of this Research Enrichment activity is to make the characterisation of light and its derived quantities (luminance… more
Amount: £45,360
Motherhood in Carceral Space: Pregnancy, Childbirth, and Maternity in Prisons and Immigration Removal Centres in England
<p style="margin-left: 0in; margin-right: 0in">This project seeks to shed light on experiences of pregnancy, childbirth, and maternity in carceral space in England &ndash; namely, within the women&rsquo;s prison estate and the immigration removal estate. The extent, albeit limited, scholarship surrounding this area has focused almost exclusively on maternal incarceration and detention as it relat… more
Amount: £108,516
Valuing fetal health outcomes in cost-effectiveness analysis
<p style="margin-left: 0cm; margin-right: 0cm">Medical interventions used in pregnancy can affect the length and quality of life of both the woman and fetus. In cost-effectiveness analysis these effects are measured using quality-adjusted life years (QALYs), but fetal outcomes are rarely measured in QALYs, despite being an important clinical outcome. This exclusion will inevitably alter the perce… more
Amount: £109,470
Liver Fluke (Opisthorchis viverrini) in Southeast Asia: Can Transmission be Halted Through Mass Drug Administration?
<p>Transmission of the human-infective and carcinogenic trematode <em>Opisthorchis viverrini</em> is ongoing in Southeast Asia. Despite decades of control,&nbsp;an estimated&nbsp;10 million people are currently infected in Thailand and Laos.&nbsp;Determining which interventions will be most effective requires an understanding of fundamental epidemiological processes, many of which are poorly unde… more
Amount: £258,595
Understanding signal modulation by the inhibitory immune checkpoints
<p style="margin-left: 0cm; margin-right: 0cm">Immune checkpoint proteins expressed on the surface of T-cells fine-tune signaling from the T-cell receptor by providing co-stimulatory and inhibitory signals. The manipulation of the receptors that provide the inhibitory signals (&lsquo;inhibitory receptors&rsquo;), using interaction-blocking and agonistic antibodies, holds great promise for treatin… more
Amount: £300,000
Evaluating prevalence, incidence rates and mortality attributable to antibiotic-resistant bacterial infections and potential biases caused by underuse of blood culture in Wahidin Hospital, a tertiary-care hospital in South Sulawesi, Indonesia
The burden of antibiotic-resistant bacterial infection (ARBI) in low and middle-income countries (LMICs) is largely unknown. Microbiology data is rarely analyzed and reported. Few publications available did not take account of bias caused by low number of blood culture utilization, categorize ARBI based on infection origin (community-onset or hospital-onset) and evaluate mortality attributable to… more
Amount: £120,000
Identifying the genetic determinants of Fusobacterium associated with diarrhoeal disease and colorectal cancer in Vietnam
The gut microbiome and its dysbiosis play a central role in understanding infectious and non-infectious conditions. Evidence suggests Fusobacterium nucleatum, an oral anaerobic bacterial pathobiont, potentiates colonic tumourigenesis. My recent work in Vietnam indicates that Fusobacterium, including F. nucleatum, is also enriched in the gut microbiome of children during infectious diarrhoea. My a… more
Amount: £223,772
Biomedical Vacation Scholarship Programme - University of Oxford
<p>This award is for 6 students per year for 5 years. It includes ?a salary at the national living wage plus holiday pay and national insurance or equivalent,?as well as?funds to cover or significantly subsidise accommodation and travel (&pound;1500 outside of London and up to &pound;2000 in London).??? It includes &pound;500 to each studentship towards research expenses.??? Unspent funds can be … more
Amount: £166,500
Spot Sepsis
Spot Sepsis is a multi-site prospective observational cohort study, conceived by the Mahidol-Oxford Tropical Medicine Research Unit (MORU) and Médecins Sans Frontières Spain (MSF SPAIN). Over 15 months, we will enroll a minimum of 4,900 children between the age of one month and five years with acute febrile illness presenting to six regional hospitals across Asia (Indonesia, Philippines, Cambodia… more
Amount: £498,240
Public Involvement in the Governance of Population Level Research
<p style="margin-left: 0cm; margin-right: 0cm">Population-level research governance is at a critical juncture. Traditional governance tools, like informed consent and expert committee review processes, have been stretched beyond their ability to function in an effort to accommodate research at scale. While consensus on the importance of involving the public&nbsp;in governance exists, there is lit… more
Amount: £29,320
Building a social science research agenda to explore the local contexts of viral hepatitis
<p style="margin-left: 0cm; margin-right: 0cm">Viral hepatitis is a global health threat that contributes to more annual deaths than HIV&nbsp;or malaria. Hepatitis B virus can be prevented by early vaccination or treated with antiviral drugs and hepatitis C virus can be cured safely and effectively with direct acting antivirals, yet screening, diagnosis and treatment remain low on a global scale.… more
Amount: £27,800
Inaugural Meeting of the Ebola Data Platform Data Access Committee
<p>The Ebola Data Platform (EDP) strengthens knowledge and capacity across the health, research and humanitarian communities to reduce the impact of Ebola through responsible data reuse. The Data Access Committee (DAC) is a key pillar of the Platform&rsquo;s governance framework, facilitating access to data from the Platform for equitable research and to&nbsp;help tackle the most pressing challen… more
Amount: £19,879
Good Financial Grant Practice/Global Grant Community
<p style="margin-left: 0cm; margin-right: 0cm">The African Academy of Sciences (AAS) is strengthening financial management of grants by developing a good financial grant ecosystem, that whilst developed in Africa is applicable to the Global Grant Community.&nbsp; By being applicable across borders, geographical regions and sectors, it will help ensure buy in and adoption by global funding agencie… more
Amount: £120,000
Understanding mental health
<p style="margin-left: 0cm; margin-right: 0cm">My proposed secondment project will assess the situation and understanding of mental health in OECD countries. Health systems have not yet adequately responded to the burden of mental disorders, resulting in a wide&nbsp;gap between the need for treatment and its provision.&nbsp;The key&nbsp;goals are to: (1)&nbsp;summarise&nbsp;the different methods … more
Amount: £13,435