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Vacation Scholarships 2018 - University of Oxford
CHIM - Shigella sonnei in Vietnamese adults - Development funds
<p>Diarrhoea remains a major cause of childhood morbidity and mortality globally. The vast majority of the 2 billion<br> annual diarrhoeal infections occur in low and middle-income countries (LMICs). Members of the genus <em>Shigella</em><br> are key agents of diarrhoea in LMICs, and <em>S. sonnei </em>is replacing <em>S. flexneri </em>as the predominant species globally.<br> There is a necessity… more
Malaria Controlled Human Infection Model - application development
<p>We wish to apply for funds to develop the malaria CHIM application. These are for a Co-investigators/stakeholders meeting to be held in Bangkok, Thailand, on 30<sup>th</sup> and 31<sup>st</sup> January 2018 and to support a writing meeting of the PIs in February 2018 in Kilifi, Kenya.</p>
Structural studies of the host-parasite interactions at the heart of malaria pathogenicity
<p>Our proposed activities consist of two major strands.</p> <p> </p> <p>Firstly we wish to take our research on tour, developing a high quality interactive stall which will allow us to present our findings to those who visit science fairs. We have secured a place at the Royal Society Summer Science Exhibition in July 2018, as the first outing for our display and this provides the deadline… more
<p>'Sacred Water' – an engagement project run by artist Lena Bui, was a creative space for researchers at OUCRU-Nepal and people living in the Kathmandu Valley to discuss health with a focus on water. However, the earthquake of 2015 caused many participants to reflect on a wider view of health. Lena became interested in what people turn to for a sense of wellbeing - cultural… more
Vacation Scholarships 2017 - University of Oxford
<p>Vacation Scholarships 2017-University of Oxford</p>
MA in History of Medicine
Health and Medicine in the Nineteenth-Century Navy.
This pilot project aims to determine the whereabouts and content of sources of potential relevance to a study of health and medicine in the nineteenth century Royal Navy. This is an extremely under-researched area. While we are aware of large bodies of rich source material, it has been impossible to evaluate fully its potential. Archives at certain institutions, such as the Naval Museum and Roy… more
Open Access Award.
Vacation Scholarships 2008.
Request for a contribution towards a meeting 'Governing Biobanks-What are the challenges?' to be held at the University of Oxford from 24-26 June 2008.
The purpose of this conference is to explore some of the complex and challenging issues that emerge from the governance of biobanks. Genomics research is on the crest of a wave, with discoveries of the variants responsible for common diseases, such as obesity and breast cancer, becoming increasingly frequent. These advances are aided by the rapid technological advances in genotyping, the accumula… more
Communication impairments in children: causes, correlates and outcomes.
Children with specific language impairment (SLI) fail to develop language at the normal rate, for no apparent cause. This programme is concerned with the causes of SLI, both in terms of underlying cognitive processes, and in terms of etiology. One theory maintains that a basic problem in auditory perception is at the root of SLI, with language difficulties as a secondary consequence. The ways … more
Investigation into the functional role of ROR-gamma T in inflammatory bowel disease models.
Mucosal immune responses are actively regulated to prevent development of harmful cell mediated immune responses, yet little is known about the cell types and cytokines involved in this regulation. Two broad approaches will be used to identify the basic mechanisms of mucosal immune regulation. In the first, a recently described murine model of colitis with similarities to Crohn's disease in man, … more
DNA origami: how do you fold a genome?
<p>Recent advances in DNA sequencing technology mean that it is now possible to identify genetic variants in patients with specific diseases which either cause or alter their risk of developing that disorder. However, linking these variants to the genes they regulate and the symptoms of the condition itself is time-consuming and challenging. The overarching aim of this project is to develop high-… more
Using genetic diversity to map fine-scale epidemiology in malaria
<p>The recent evolution of artemisin-resistant strains of P.falciparum in Southeast Asia have highlighted the need for a deeper understanding of the genetic epidemiology of malaria and for more strategic implementation of malaria control resources. Assessment of the efficacy of these control efforts requires accurate and standardised estimates of epidemological parameters, such as transmission in… more
Statistical models of gene-environment interactions
<p>This PhD focuses on developing statistical methods to discover gene – environment (G-E) interactions. To date there has been some interest in testing for G-E interactions in animal models, but limited success in uncovering examples of G-E interactions in humans. This is in part due to the problem of exposure assessment, or rather, because representative data on the environment of a numbe… more
Open Research: Thailand Major Overseas Programme 2015 - 2020
<p style="margin-left: 0cm; margin-right: 0cm">This application is led by Phaik Yeong Cheah, the head of Bioethics & Engagement and co-led by Naomi Waithira, the head of Data Management and supported by Nicholas Day, the Director of the Programme. </p> <p style="margin-left: 0cm; margin-right: 0cm">Upon successful completion of the activity, we would have achieved the following:</p> <p… more
Planning meeting for Lancet Commission on Diagnosis
<p>The Lancet Commission on Diagnosis</p> <p>Phase 1 - Planning Meeting</p> <p>Following the publication of The Lancet Series on Pathology in Low and Middle Income countries in March, the Lancet asked me to lead a Lancet Commisison on Diagnosis (Pathology and Laboratory Medicine and Imaging). </p> <p>There will be two phases. The first will be a 1.5 day face-to-face… more
Expanding the Inventory Records and Online Profile of Early Modern Medical Books at the Science Museum
<p>The short-term goal of my six-month project is to create a new inventory of the Science Museum’s 158 pre-1800 medical books which would contain more up-to-date, detailed information about the contents, physical format and publication circumstances of the predominantly Latin and English codices. I also intend to explore and document links between the books and the museum’s large col… more
Returning research results: a Northern European Research Network
<p>The generation of (clinically significant) research results in biobanking and other research activities raises questions about return of these findings, such as: should researchers return this information to participants, and if so, what, when and how should it be returned? While some bioethicists argue that researchers have a duty to return some clinically significant results, in practice thi… more