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Search results (Displaying 66 grants)

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Earliest award date
31 Jan 2017
Latest award date
13 Nov 2019
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Human sensitivity to short-wavelength light in non-image-forming vision: Toward a mechanistic understanding of the impact of blue light on sleep and circadian rhythms
<p>In chronobiology and sleep research, a significant proportion of past research studies examining the effects of light on the acute suppression of melatonin and on circadian photoentrainment have exclusively examined male participants, or naturally cycling female participants. The basis for this bias in participant recruitment is empirical evidence that the production of melatonin may be modula… more
Amount: £20,000
Function of novel human T cell subsets in host defence
<p>We are organising an international meeting on unconventional T cells (CD1-MR1: beyond MHC restricted lymphocytes). This is the major meeting for groups investigating these important components of immunity and occurs every 2 years, lasting 4 days. The aim of this proposal is to help support initiatives within this meeting to enhance diversity and inclusion. These include: Bursaries for those wi… more
Amount: £19,000
Amount: £11,000
CHIM - Shigella sonnei in Vietnamese adults - Development funds
<p>Diarrhoea remains a major cause of childhood morbidity and mortality globally. The vast majority of the 2 billion<br> annual diarrhoeal infections occur in low and middle-income countries (LMICs). Members of the genus <em>Shigella</em><br> are key agents of diarrhoea in LMICs, and <em>S. sonnei </em>is replacing <em>S. flexneri </em>as the predominant species globally.<br> There is a necessity… more
Amount: £21,120
Malaria Controlled Human Infection Model - application development
<p>We wish to apply for funds to develop the malaria CHIM application. These are for a Co-investigators/stakeholders meeting to be held in Bangkok, Thailand, on 30<sup>th</sup> and 31<sup>st</sup> January 2018 and to support a writing meeting of the PIs in February 2018 in Kilifi, Kenya.</p>
Amount: £22,186
Amount: £12,456
Structural studies of the host-parasite interactions at the heart of malaria pathogenicity
<p>Our proposed activities consist of two major strands.</p> <p>&nbsp;</p> <p>Firstly we wish to take our research on tour, developing a high quality interactive stall which will allow us to present our findings to those who visit science fairs. We have secured a place at the Royal Society Summer Science Exhibition in July 2018, as the first outing for our display and this provides the deadline… more
Amount: £49,000
Discretionary Award
<p>'Sacred Water' &ndash; an engagement project run by artist Lena Bui, was a creative space for researchers at OUCRU-Nepal and people living in the Kathmandu Valley to discuss health with a focus on water.&nbsp; However, the earthquake of 2015 caused many participants to reflect&nbsp;on a wider view of health. Lena became interested in what people turn to for a sense of wellbeing&nbsp;- cultural… more
Amount: £40,000
Vacation Scholarships 2017 - University of Oxford
<p>Vacation Scholarships 2017-University of Oxford</p>
Amount: £15,500
Human sensitivity to short-wavelength light in non-image-forming vision: Toward a mechanistic understanding of the impact of blue light on sleep and circadian rhythms
Measurement and characterisation of light — whether it is in everyday contexts or in experimental and research settings — is notoriously non-trivial. Part of this is due to the complexity of the underlying concepts (e.g. measurement geometry, propagation of light in space). The goal of this Research Enrichment activity is to make the characterisation of light and its derived quantities (luminance… more
Amount: £45,360
DNA origami: how do you fold a genome?
<p>Recent advances in DNA sequencing technology mean that it is now possible to identify genetic variants in patients with specific diseases which either cause or alter their risk of developing that disorder. However, linking these variants to the genes they regulate and the symptoms of the condition itself is time-consuming and challenging. The overarching aim of this project is to develop high-… more
Amount: £35,850
Using genetic diversity to map fine-scale epidemiology in malaria
<p>The recent evolution of artemisin-resistant strains of P.falciparum in Southeast Asia have highlighted the need for a deeper understanding of the genetic epidemiology of malaria and for more strategic implementation of malaria control resources. Assessment of the efficacy of these control efforts requires accurate and standardised estimates of epidemological parameters, such as transmission in… more
Amount: £0
Statistical models of gene-environment interactions
<p>This PhD focuses on developing statistical methods to discover gene &ndash; environment (G-E) interactions. To date there has been some interest in testing for G-E interactions in animal models, but limited success in uncovering examples of G-E interactions in humans. This is in part due to the problem of exposure assessment, or rather, because representative data on the environment of a numbe… more
Amount: £0
Public Involvement in the Governance of Population Level Research
<p style="margin-left: 0cm; margin-right: 0cm">Population-level research governance is at a critical juncture. Traditional governance tools, like informed consent and expert committee review processes, have been stretched beyond their ability to function in an effort to accommodate research at scale. While consensus on the importance of involving the public&nbsp;in governance exists, there is lit… more
Amount: £29,320
Building a social science research agenda to explore the local contexts of viral hepatitis
<p style="margin-left: 0cm; margin-right: 0cm">Viral hepatitis is a global health threat that contributes to more annual deaths than HIV&nbsp;or malaria. Hepatitis B virus can be prevented by early vaccination or treated with antiviral drugs and hepatitis C virus can be cured safely and effectively with direct acting antivirals, yet screening, diagnosis and treatment remain low on a global scale.… more
Amount: £27,800
Inaugural Meeting of the Ebola Data Platform Data Access Committee
<p>The Ebola Data Platform (EDP) strengthens knowledge and capacity across the health, research and humanitarian communities to reduce the impact of Ebola through responsible data reuse. The Data Access Committee (DAC) is a key pillar of the Platform&rsquo;s governance framework, facilitating access to data from the Platform for equitable research and to&nbsp;help tackle the most pressing challen… more
Amount: £19,879
Understanding mental health
<p style="margin-left: 0cm; margin-right: 0cm">My proposed secondment project will assess the situation and understanding of mental health in OECD countries. Health systems have not yet adequately responded to the burden of mental disorders, resulting in a wide&nbsp;gap between the need for treatment and its provision.&nbsp;The key&nbsp;goals are to: (1)&nbsp;summarise&nbsp;the different methods … more
Amount: £13,435
Establishing global ethical norms on Minimally Invasive Autopsy
<p>Uncertainty about causes of death and unregistered mortality patterns in low-middle income countries (LMICs) are limitations to planning and evaluation of health programmes. Funding bodies such as the Gates Foundation have advocated Minimally Invasive Autopsy (MIA) to address these important kinds of uncertainty and to minimise sensitivities. MIA involves using hollow needles to sample a numbe… more
Amount: £29,500
Health of the Arts
<p>The proposed project takes up the message of arts access charity Arts Emergency to ask 'is an arts emergency a health emergency?' and also to ask the question of who gets to access the arts from an interdisciplinary perspective.</p> <p>Recent medical humanities research shows us that the arts have a critical role to play in health and wellbeing, both at an individual level and in terms of soc… more
Amount: £16,954
Human Infection Studies
<p style="margin-left: 0cm; margin-right: 0cm">Bacillary diarrhoea, including dysentery, due to <em>Shigella</em> causes a high burden of disease in low-and-middle income countries (LMICs), where 70% of all cases occur in children under 5 years. Children in this age group form the target population for disease prevention through vaccination. However, there are no licensed <em>Shigella</em> vaccin… more
Amount: £28,984