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Your search ‘’ returned 30 results in ‘All grant fields’

Search results (Displaying 30 grants)

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Earliest award date
31 Jan 2017
Latest award date
15 Nov 2018
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Amount: £11,000
CHIM - Shigella sonnei in Vietnamese adults - Development funds
<p>Diarrhoea remains a major cause of childhood morbidity and mortality globally. The vast majority of the 2 billion<br> annual diarrhoeal infections occur in low and middle-income countries (LMICs). Members of the genus <em>Shigella</em><br> are key agents of diarrhoea in LMICs, and <em>S. sonnei </em>is replacing <em>S. flexneri </em>as the predominant species globally.<br> There is a necessity… more
Amount: £21,120
Malaria Controlled Human Infection Model - application development
<p>We wish to apply for funds to develop the malaria CHIM application. These are for a Co-investigators/stakeholders meeting to be held in Bangkok, Thailand, on 30<sup>th</sup> and 31<sup>st</sup> January 2018 and to support a writing meeting of the PIs in February 2018 in Kilifi, Kenya.</p>
Amount: £22,186
Structural studies of the host-parasite interactions at the heart of malaria pathogenicity
<p>Our proposed activities consist of two major strands.</p> <p>&nbsp;</p> <p>Firstly we wish to take our research on tour, developing a high quality interactive stall which will allow us to present our findings to those who visit science fairs. We have secured a place at the Royal Society Summer Science Exhibition in July 2018, as the first outing for our display and this provides the deadline… more
Amount: £49,000
Discretionary Award
<p>'Sacred Water' &ndash; an engagement project run by artist Lena Bui, was a creative space for researchers at OUCRU-Nepal and people living in the Kathmandu Valley to discuss health with a focus on water.&nbsp; However, the earthquake of 2015 caused many participants to reflect&nbsp;on a wider view of health. Lena became interested in what people turn to for a sense of wellbeing&nbsp;- cultural… more
Amount: £40,000
Vacation Scholarships 2017 - University of Oxford
<p>Vacation Scholarships 2017-University of Oxford</p>
Amount: £15,500
DNA origami: how do you fold a genome?
<p>Recent advances in DNA sequencing technology mean that it is now possible to identify genetic variants in patients with specific diseases which either cause or alter their risk of developing that disorder. However, linking these variants to the genes they regulate and the symptoms of the condition itself is time-consuming and challenging. The overarching aim of this project is to develop high-… more
Amount: £35,850
Open Research: Thailand Major Overseas Programme 2015 - 2020
<p style="margin-left: 0cm; margin-right: 0cm">This application is led by Phaik Yeong Cheah, the head of Bioethics &amp; Engagement and co-led by Naomi Waithira, the head of Data Management and supported by Nicholas Day, the Director of the Programme.&nbsp;</p> <p style="margin-left: 0cm; margin-right: 0cm">Upon successful completion of the activity, we would have achieved the following:</p> <p… more
Amount: £49,257
Planning meeting for Lancet Commission on Diagnosis
<p>The Lancet Commission on Diagnosis</p> <p>Phase 1 - Planning Meeting</p> <p>Following the publication of The&nbsp;Lancet Series on Pathology in Low and Middle Income &nbsp;countries in March, the Lancet asked me&nbsp;to lead a Lancet Commisison on Diagnosis (Pathology and Laboratory Medicine and Imaging). &nbsp;</p> <p>There will be two phases. &nbsp;The first will be a 1.5 day face-to-face… more
Amount: £8,000
Expanding the Inventory Records and Online Profile of Early Modern Medical Books at the Science Museum
<p>The short-term goal of my six-month project is to create a new inventory of the Science Museum&rsquo;s 158 pre-1800 medical books which would contain more up-to-date, detailed information about the contents, physical format and publication circumstances of the predominantly Latin and English codices. I also intend to explore and document links between the books and the museum&rsquo;s large col… more
Amount: £13,005
Returning research results: a Northern European Research Network
<p>The generation of (clinically significant) research results in biobanking and other research activities raises questions about return of these findings, such as: should researchers return this information to participants, and if so, what, when and how should it be returned? While some bioethicists argue that researchers have a duty to return some clinically significant results, in practice thi… more
Amount: £29,975
Defining the innate-like mucosal T cell response to bacterial infection in airways disease
<p>Exacerbations cause most morbidity, mortality and economic costs of asthma. Most are driven by infections and constitute a significant unmet clinical need, particularly in non-eosinophilic disease. The 2017 AMAZES trial showed azithromycin reduced exacerbations in severe asthma, but raises several critical questions, especially, the relevant mechanisms of action, whether anti-microbial, anti-i… more
Amount: £25,000
Dengue Controlled Human Infection Model - Development Grant
<p>Following a positive response to the&nbsp;preliminary submission for grant funding&nbsp;to&nbsp;establish a Dengue Controlled Human Infection Model (Dengue-CHIM )&nbsp;in Ho Chi Minh City, Vietnam, I am submitting this request&nbsp;for a small grant&nbsp;to assist in refining and&nbsp;developing the main proposal prior to&nbsp;final&nbsp;submission in March 2018.</p> <p>&nbsp;</p> <p>During … more
Amount: £23,690
Medicine Quality and Public Health Conference 2018
<p>Globally, medicine regulatory authorities, research groups, international organisations, law enforcement agencies and other key stakeholders, including the pharmaceutical industry, are trying to keep patients safe and ensure that the benefits of modern medicine are delivered to patients. However, organisations working in this field tend to be fragmented with the wide diversity of professionals… more
Amount: £24,000
Facing ethics: Identifying ethical issues in computational phenotyping research
<p>Computational phenotyping research uses big data methods to refine the diagnosis of rare genetic diseases. Photographs (and other biomedical data) of people with genetic syndromes are used to train machine-learning algorithms to identify the phenotypic features associated with different disorders. The data are obtained from consortia of clinicians and researchers involved in rare disease resea… more
Amount: £27,408
Improving health outcomes for looked after children and young people
<p>Previous research suggests that looked after children are less likely to be treated in the way that the statutory guidance on promoting the health and well-being of looked after children recommends, and that they receive worse healthcare in comparison to their non-looked after peers. They also have worse experiences of the health service, and due to complex and time consuming policies and proc… more
Amount: £8,010
Epidemiology and health burdens of antimicrobial resistant bacterial infection in Southeast Asia and impact of antibiotic use on patient survival
<p>Epidemiology of drug-resistant infection (DRI) and impact of antibiotic use on patient mortality remain largely unknown in Southeast Asia. Correction factors are crucial to estimate the total deaths attributable to DRI when only mortality of patients with bacteraemia&nbsp;is known. The correction factors are available for developed country and not for developing country. I aim to establish cor… more
Amount: £18,800
Stochastic variation and regulation of bacterial DNA repair and mutagenesis
<p>Studying the molecular mechanisms of mutagenesis is crucial to understanding genome evolution and the emergence of drug resistance in pathogens. It is known that cellular stress responses increase mutation rates after DNA damage and antimicrobial treatment. Recent evidence suggests that stochastic effects play key roles in these responses, causing cell-to-cell variation in mutation rates and d… more
Amount: £25,000
All-optical interrogation of neural circuits during behaviour
<p>Neural circuits display complex spatiotemporal patterns of activity on the millisecond timescale. Understanding how these activity patterns drive behaviour is a fundamental problem in neuroscience. To address this challenge, I have recently introduced a novel approach that combines simultaneous two-photon calcium imaging and two-photon targeted optogenetic photostimulation with the use of a sp… more
Amount: £25,000
Investigating the role of Kv1.6 in pain pathways
<p>Kv1.6 is a member of the Shaker-like Kv1 potassium channel protein family. Widely expressed in the nervous system, these channels have delayed outward rectifier properties and evidence indicates that they act to suppress action potential firing. In the field of neuropathic pain, of which neuronal hyperexcitabilty is a common hallmark, these channels are of interest as their malfunction or down… more
Amount: £29,760