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Search results (Displaying 176 grants)

Total grants
176
Total funders
1
Total recipients
1
Earliest award date
24 Jan 2017
Latest award date
05 Dec 2018
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In Their Own Voices: Vulnerabilities & Abilities of Women, Children, & Families in Health Research
<p>As REACH enters its second year, we have an exciting opportunity to use our early findings and to expand our use of visual methods to spark wider community and public debate about the ethical issues arising in research with women, children&nbsp;and their families in contexts of poverty and gender inequality. This proposal complements existing Africa and Asia Programme provisions for public eng… more
Amount: £140,079
Amount: £150,000
Amount: £11,000
An Extended Pilot for the Human Cell Atlas: Adult tissues, human development and inflammation-mediated pathologies
<p>The Human Cell Atlas (HCA) is an international, collaborative effort that &ldquo;&hellip;aims to define all human cell types in terms of their distinctive patterns of gene expression, physiological states, developmental trajectories, and location&rdquo;.</p> <p>&nbsp;</p> <p>Here, we will contribute directly to the first phase of the HCA by forming an &lsquo;extended pilot&rsquo; to implemen… more
Amount: £389,335
Flexible task representations for intelligent behavior
<p>A long research tradition in cognitive neuroscience has investigated the role of the prefrontal cortex (PFC) in flexible goal-directed behaviour. This work has yielded important insights, e.g., that the PFC&rsquo;s coding properties flexibly adapt when task demands change&nbsp;to prioritise goal-relevant information. However,&nbsp;it relies primarily upon the use&nbsp;of familiar and explicitl… more
Amount: £250,000
Metabolic Characterization of Natural Killer T Cell responses to sterile, hypoxic injury
<p>It has been described that&nbsp;ischemia-reperfusion injury (IRI), such as during&nbsp;organ transplantation,&nbsp;evokes damaging sterile inflammation and secondary tissue injury that is&nbsp;dependent on iNKT cell activation, but the underlying mechanisms remain elusive.&nbsp;Similarly, in sickle cell disease (SCD)&nbsp;mice,&nbsp;RBC sickling and widely disseminated microvascular ischemia&n… more
Amount: £250,000
CHIM - Shigella sonnei in Vietnamese adults - Development funds
<p>Diarrhoea remains a major cause of childhood morbidity and mortality globally. The vast majority of the 2 billion<br> annual diarrhoeal infections occur in low and middle-income countries (LMICs). Members of the genus <em>Shigella</em><br> are key agents of diarrhoea in LMICs, and <em>S. sonnei </em>is replacing <em>S. flexneri </em>as the predominant species globally.<br> There is a necessity… more
Amount: £21,120
Malaria Controlled Human Infection Model - application development
<p>We wish to apply for funds to develop the malaria CHIM application. These are for a Co-investigators/stakeholders meeting to be held in Bangkok, Thailand, on 30<sup>th</sup> and 31<sup>st</sup> January 2018 and to support a writing meeting of the PIs in February 2018 in Kilifi, Kenya.</p>
Amount: £22,186
Amount: £100,000
Amount: £85,000
Understanding the relationship between apnoeas and brain function in premature infants
<p>Apnoea of prematurity is a common problem in neonatal care, affecting all preterm infants born before 29 weeks&rsquo; gestation. These potentially life-threatening events are associated with pronounced physiological instability, reduced cerebral oxygenation, and long-term consequences including reduced cognitive ability in childhood. However, it is unclear how these frequent intermittent episo… more
Amount: £841,963
Circuit Mechanisms of Learning and Decision Making
<p>Decision making concerns every aspect of our lives. Despite substantial progress in understanding the brain regions involved in learning and decision making, the neuronal circuits that govern choice behaviour have remained elusive. This proposal aims at studying precise neuronal circuits underlying learning and decision making. We will focus on frontostriatal neuronal circuits, and how neuromo… more
Amount: £1,178,460
Structural studies of the host-parasite interactions at the heart of malaria pathogenicity
<p>Our proposed activities consist of two major strands.</p> <p>&nbsp;</p> <p>Firstly we wish to take our research on tour, developing a high quality interactive stall which will allow us to present our findings to those who visit science fairs. We have secured a place at the Royal Society Summer Science Exhibition in July 2018, as the first outing for our display and this provides the deadline… more
Amount: £49,000
Implementation of ISARICC's 2018-2022 Strategic Plan
<p>Bridging funds for transition to ISARICC's 2018-2022 Strategic Plan</p>
Amount: £144,634
Discretionary Award
<p>'Sacred Water' &ndash; an engagement project run by artist Lena Bui, was a creative space for researchers at OUCRU-Nepal and people living in the Kathmandu Valley to discuss health with a focus on water.&nbsp; However, the earthquake of 2015 caused many participants to reflect&nbsp;on a wider view of health. Lena became interested in what people turn to for a sense of wellbeing&nbsp;- cultural… more
Amount: £40,000
Development of compounds that inhibit RAS-effector protein-protein interactions in cancer using a single antibody domain drug surrogate emulator approach
Prof Rabbitts and colleagues from the Weatherall Institute of Molecular Biology have been awarded Seeding Drug Discovery funding to develop small molecules specifically targeting the RAS-effector protein-protein interactions. The RAS family of oncogenes is among the most frequently mutated in human cancers. Using minimal antibody fragments, the group has characterized an anti-RAS VH segment whos… more
Amount: £98,762
Vacation Scholarships 2017 - University of Oxford
<p>Vacation Scholarships 2017-University of Oxford</p>
Amount: £15,500
Neuroscience
Not available
Amount: £2,980,000
Amount: £2,460,000