How do separate populations of stem cellsinfluence each other in the visual system of the zebrafish? (360G-Wellcome-089594_Z_09_Z)
1) To investigate how various retinal inputs influence the growth of the optic tectum. How does a lack of retinal input alter the size, shape, proliferation and cellular organization of the tectum? What are the consequences for tectal proliferation and differentiation when retinal ganglion (RGC) axonal activity is abrogated? How does a lack of retinal input affect the pathways that regulate neurogenesis in the optic tectum? 2) To investigate how signalling between the retina and the tectum controls growth and shifting connections. Is the secreted Sonic hedghog (Shh) protein transmitted along retinal ganglion cell axons to the tectum? How does axonal transport of signalling molecules affect growth and differentiation in the optic tectum?
Where is this data from?
This data was originally published by The Wellcome Trust. If you see something about your organisation or the funding it has received on this page that doesn't look right you can submit a grantee amendment request. You can hover over codes from standard codelists to see the user-friendly name provided by 360Giving.
Grant Details
| Region | London |
| Award Date | 2008-12-16T00:00:00+00:00 |
| Sponsor(s) | Prof Claudio Stern |
| Internal ID | 089594/Z/09/Z |
| Planned Dates: End Date | 2013-09-30T00:00:00+00:00 |
| Planned Dates: Start Date | 2009-09-28T00:00:00+00:00 |
| Amount Awarded | 203295 |
| Financial Year | 2008/09 |
| Lead Applicant | Ms Hannah L Rouse |
| Grant Programme: Title | PhD Studentship (Basic) |
| Applicant Surname | Rouse |
| Approval Committee | Molecules, Genes and Cells Funding Committee |
| Recipient Org: Country | United Kingdom |
| Recipient Org: City | London |
| Has the grant transferred? | No |
| Research conducted at multiple locations? | No |
| Total amount including partnership funding | 203295 |