Neuronal and glial energy use and supply (360G-Wellcome-097265_Z_11_A)
Processing and propagation of information by neurons is energetically expensive. We will investigate the following aspects of energy supply and demand in the grey and white matter of brain slices: (1) how sodium pumping by neurons (which consumes most brain ATP) is regulatedin response to sodium load and is related to oxygen consumption, (2) how a lowered energy supply affects information transfer across synapses, (3) which cortical synapses are mainly responsible for increasing energy supply when neurons are active, and (4) how energy is supplied to developing oligodendrocytes (glial cells) duringmyelination.
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Grant Details
| Amount Awarded | 8500 |
| Applicant Surname | Engl |
| Approval Committee | PhD Studentships |
| Award Date | 2013-02-11T00:00:00+00:00 |
| Financial Year | 2012/13 |
| Grant Programme: Title | PhD Studentship (Basic) |
| Internal ID | 097265/Z/11/A |
| Lead Applicant | Ms Elisabeth Engl |
| Partnership Value | 8500 |
| Planned Dates: End Date | 2015-09-30T00:00:00+00:00 |
| Planned Dates: Start Date | 2012-10-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | Greater London |
| Sponsor(s) | Prof David Attwell |