Investigating the role of adult neurogenesis and theglutamate transmission in the pathophysiology and treatment of depression. (360G-Wellcome-077701_Z_05_A)
Investigating the role of adult neurogenesis and glutamate transmission in the pathophysiology and treatment of depression Recent evidence suggests that a deficit in adult hippocampal neurogenesis may be critically involved in the pathophysiology of depression and that neurogenic activation may underlie the therapeutic efficacy of a number of antidepressant treatments. The aim of this project is to combine molecular, pharmacological, behavioural and genetic approaches to further investigate the neurogenic hypothesis, and provide a better understanding of the role of the glutamate system in its regulation. This research will increase our understanding of mood disorder aetiology and may provide vital information for the development of much needed novel and improved therapeutic strategies.
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Grant Details
| Amount Awarded | 26153 |
| Applicant Surname | Groves |
| Approval Committee | Neurosciences And Mental Health |
| Award Date | 2006-10-12T00:00:00+00:00 |
| Financial Year | 2006/07 |
| Grant Programme: Title | PhD Studentship (Basic) |
| Internal ID | 077701/Z/05/A |
| Lead Applicant | Mr James Groves |
| Partnership Value | 26153 |
| Planned Dates: End Date | 2009-09-30T00:00:00+00:00 |
| Planned Dates: Start Date | 2006-10-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | South East |
| Sponsor(s) | Dr Jeremy Taylor |