PhD Training Programme for Clinicians at the University of Cambridge: 'Neural and molecular mechanisms involved in human obesity'. (360G-Wellcome-087008_Z_08_Z)
Body mass is highly heritable and a number of genes have been identified, in which mutations lead to severe early onset obesity. The aim of my research is to investigate the molecular mechanisms involved in mediating the effects of the adipocyte derived hormone leptin on fertility through the study of naturally occurring mutations in the leptin receptor. I will also investigate the functional effects of a new obesity candidate gene, neuronal growth regular 1. These studies will provide a sound training in biochemistry and molecular biology and provide the basis for exploring the biology of novel candidates emerging from hypothesis-free approaches.
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Grant Details
| Region | East of England |
| Award Date | 2008-07-15T00:00:00+00:00 |
| Sponsor(s) | Prof David Lomas |
| Internal ID | 087008/Z/08/Z |
| Planned Dates: End Date | 2011-08-17T00:00:00+00:00 |
| Planned Dates: Start Date | 2008-08-18T00:00:00+00:00 |
| Amount Awarded | 197154 |
| Financial Year | 2007/08 |
| Lead Applicant | Dr Shwetha Ramachandrappa |
| Grant Programme: Title | PhD Training Fellowship for Clinicians |
| Applicant Surname | Ramachandrappa |
| Approval Committee | Neurosciences And Mental Health |
| Recipient Org: Country | United Kingdom |
| Recipient Org: City | Cambridge |
| Has the grant transferred? | No |
| Research conducted at multiple locations? | No |
| Total amount including partnership funding | 197154 |