PhD Training Programme for Clinicians at the University of Cambridge: 'Neural and molecular mechanisms involved in human obesity'. (360G-Wellcome-087008_Z_08_Z)

£197,154

Body mass is highly heritable and a number of genes have been identified, in which mutations lead to severe early onset obesity. The aim of my research is to investigate the molecular mechanisms involved in mediating the effects of the adipocyte derived hormone leptin on fertility through the study of naturally occurring mutations in the leptin receptor. I will also investigate the functional effects of a new obesity candidate gene, neuronal growth regular 1. These studies will provide a sound training in biochemistry and molecular biology and provide the basis for exploring the biology of novel candidates emerging from hypothesis-free approaches.

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Grant Details

Amount Awarded 197154
Applicant Surname Ramachandrappa
Approval Committee Neurosciences And Mental Health
Award Date 2008-07-15T00:00:00+00:00
Financial Year 2007/08
Grant Programme: Title PhD Training Fellowship for Clinicians
Internal ID 087008/Z/08/Z
Lead Applicant Dr Shwetha Ramachandrappa
Partnership Value 197154
Planned Dates: End Date 2011-08-17T00:00:00+00:00
Planned Dates: Start Date 2008-08-18T00:00:00+00:00
Recipient Org: Country United Kingdom
Region East of England
Sponsor(s) Prof David Lomas