Modernising Medical Microbiology: Establishing how new technologies can be optimally integrated into microbiology. (360G-Wellcome-087646_Z_08_Z)

This proposal should lead to a comprehensive web-based tool managed by the HPA which microbiologists in NHS Trusts could use to harness genomics in optimising management of local infection control and halting transmission of major pathogens. It will also provide a data/sample repository which national researchers could exploit, in conjunction with those at the cutting edge of bioinformatics, to elucidate host pathogen interactions and thus identify future targets for medical or strategic interventions. The programme of work will produce more complete descriptions of routes of pathogen transmission, which will lead to improvements in current guidelines for infection control. In terms of leadership and training, the Consortium will mature a group of young researchers excited about the genomic revolution, who have seen the techniques applied successfully and are now ready and want to go and do it themselves. These individuals will be key future leaders in microbiology and infectious diseases.