The impact of murine norovirus infection on the innate immune system. (360G-Wellcome-089214_Z_09_B)
We propose that the activation of innate immune responses become altered upon infection with persistent versus non-persistent strains of MNV. We further propose that persistent MNV infection affects subsequent immune responses to other pathogens such as Salmonella. 1. To identify the signaling pathways of the innate immune system involved in the response to persistent and non-persistent variants of murine norovirus, focusing particularly on pathways that may be implicated in the production of type 1 interferons. 2. To determine whether persistent MNV infection affects the subsequent immune responses to other enteric pathogens such as Salmonella
Where is this data from?
This data was originally published by The Wellcome Trust. If you see something about your organisation or the funding it has received on this page that doesn't look right you can submit a grantee amendment request. You can hover over codes from standard codelists to see the user-friendly name provided by 360Giving.
Grant Details
| Amount Awarded | 18300 |
| Applicant Surname | Chettle |
| Approval Committee | PhD Studentships |
| Award Date | 2013-12-17T00:00:00+00:00 |
| Financial Year | 2013/14 |
| Grant Programme: Title | PhD Studentship (Basic) |
| Internal ID | 089214/Z/09/B |
| Lead Applicant | Mr Alexander Chettle |
| Partnership Value | 18300 |
| Planned Dates: End Date | 2014-07-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2013-10-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | East of England |
| Sponsor(s) | Prof Paul Lehner |