The use of embryonic dopaminergic tissues for Parkinson's Disease transplantation therapy. (360G-Wellcome-089638_Z_09_Z)
Overall aim: Improve dopamine cell yield and function in Parkinson's disease transplantation therapy (in rats) . Objective 1: Investigate the time course of dopamine neuron development in-vitro and in dopamine grafts. Objective 2: Characterise cell populations in rat and human embryonic dopamine grafts in a rat model of PD. Objective 3: Improve the survival of rat and human embryonic dopamine grafts and cultures. Objective 4: Determine the embryonic donor age in human embryos from which > 50% survival can be obtained (equivalent to E12 in rats).
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Grant Details
Amount Awarded | 141950 |
Applicant Surname | Fjodorova |
Approval Committee | Neurosciences And Mental Health |
Award Date | 2009-07-21T00:00:00+00:00 |
Financial Year | 2008/09 |
Grant Programme: Title | PhD Studentship (Basic) |
Internal ID | 089638/Z/09/Z |
Lead Applicant | Miss Marija Fjodorova |
Partnership Value | 141950 |
Planned Dates: End Date | 2013-09-30T00:00:00+00:00 |
Planned Dates: Start Date | 2009-10-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | Wales |
Sponsor(s) | Prof Vincenzo Crunelli |