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Timing expectations in the human brain. (360G-Wellcome-089903_Z_09_Z)

We have come to understand that perception is a highly proactive process, biased to deliver the events that are most relevant to our current motivational state and task goals. Attention research has shown how signals coding predictions about the location, identity or simple features of relevant events can influence several stages of neural processing. Though expectations about the timing of events are also pervasive, the temporal dimension has been left out of mainstream research. The experiment s proposed redress this imbalance by investigating the neural systems and neural mechanisms by which temporal expectation modulates information processing and influences top-down modulation by other types of attention. In order to understand whether temporal expectation operates through a modality-independent set of mechanisms, direct comparisons will be made between effects within the visual and auditory modalities, as well as across modalities. Nine experiments are proposed, using systematic m anipulations of temporal and other types of expectations (Series 1) and of sensory modalities (Series 2). In order to reveal the neural systems and mechanisms with high spatial and temporal resolution, and to test for their causal role; the methodology includes complementary hemodynamic (fMRI) and magneto/electrophysiological (MEG/EEG) brain-imaging methods, complemented by non-invasive transcranial magnetic stimulation (TMS).

£243,590

08 Oct 2009

Grant details
Amount Awarded 243590
Applicant Surname Nobre
Approval Committee Cognitive and Higher Systems Funding Committee
Award Date 2009-10-08T00:00:00+00:00
Financial Year 2009/10
Grant Programme: Title Project Grant
Internal ID 089903/Z/09/Z
Lead Applicant Prof Anna Christina Nobre
Planned Dates: End Date 2014-03-31T00:00:00+00:00
Planned Dates: Start Date 2010-10-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South East
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