Structural Molecular Biology Infrastructure for the Astbury Centre at Leeds. (360G-Wellcome-094232_Z_10_Z)

£700,000

We are seeking 1M in funding from the Wellcome Trust to provide essential infrastructure and facilities in structural biology. These will build on our existing strengths in the interdisciplinary Astbury Centre for Structural Molecular Biology (ASCMB). This money will be matched by a 1.161 investment by the University, reflecting the central roles structural and quantitative functional studies play in the emerging fields of systems and synthetic biology, and their potential contributions to wid er societal needs. The specific aims of this proposal are: 1. To provide advanced facilities for structural biology (macromolecular crystallography, negative stain electron microscopy and nuclear magnetic resonance spectroscopy) that will enable us to generate detailed structural information central to understanding the molecular basis of living processes 2. To underpin these facilities with iso-thermal calorimetry and circular dichroism spectroscopy, complementing our existing suite of bio physical techniques, to ensure that our systems of study are in a physiologically relevant and functional state for structural studies.

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Grant Details

Amount Awarded 700000
Applicant Surname Stockley
Approval Committee Molecules, Genes and Cells Funding Committee
Award Date 2011-03-09T00:00:00+00:00
Financial Year 2010/11
Grant Programme: Title Equipment & Resources: Inactive Scheme
Internal ID 094232/Z/10/Z
Lead Applicant Prof Peter Stockley
Other Applicant(s) Dr Stanley Burgess, Prof Arwen Pearson, Prof Sheena Radford, Prof Steven Homans
Partnership Value 700000
Planned Dates: End Date 2016-03-31T00:00:00+00:00
Planned Dates: Start Date 2011-04-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Yorkshire and the Humber