Studies of immunopathogenesis in dengue virus infection. (360G-Wellcome-095541_A_11_Z)
Dengue virus is transmitted to man following a bite from an infected mosquito. Although most dengue infections are relatively mild, it can lead to the more severe disease, dengue haemorrhagic fever. One of the interesting features of dengue is that there are four different viruses and immunity to one infection does not lead to immunity to the others meaning that secondary infections are common. Patients are more likely to develop symptoms during these secondary infections as opposed to their fir st infection implying some aspect of the immune response drives more severe disease. This projects aims to gain a greater understanding of the immune enhancement of disease and also to research strategies to design better vaccines to dengue.
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Grant Details
| Region | South East |
| Award Date | 2011-05-10T00:00:00+00:00 |
| Internal ID | 095541/A/11/Z |
| Planned Dates: End Date | 2021-03-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2012-10-01T00:00:00+00:00 |
| Amount Awarded | 2839596 |
| Financial Year | 2010/11 |
| Lead Applicant | Prof Gavin Robert Screaton |
| Grant Programme: Title | Investigator Award in Science |
| Applicant Surname | Screaton |
| Approval Committee | Science Interview Panel |
| Recipient Org: Country | United Kingdom |
| Recipient Org: City | Oxford |
| Has the grant transferred? | Yes |
| Research conducted at multiple locations? | Yes |
| Total amount including partnership funding | 2839596 |