Development, plasticity, energy supply and pathology of myelinated axons (360G-Wellcome-099691_Z_12_Z)

£198,333

The white matter of the CNS allows rapid transmission of information at low energetic cost. Despite its importance for brain function, the development, plasticity, energetics and pathology of the white matter are poorly understood. We will investigate, in vitro in brain slices and in vivo in zebrafish: (1) how electrical activity in oligodendrocyte precursors regulates myelination; (2) mechanisms underlying the tuning of conduction speed of myelinated axons; (3) mechanisms localising mitochondria in oligodendrocyte lineage cells; (4) how microglia survey the white matter in health and disease.

Where is this data from?

This data was originally published by The Wellcome Trust. If you see something about your organisation or the funding it has received on this page that doesn't look right you can submit a grantee amendment request. You can hover over codes from standard codelists to see the user-friendly name provided by 360Giving.

Grant Details

Amount Awarded 198333
Applicant Surname Krasnow
Approval Committee PhD Studentships
Award Date 2012-03-19T00:00:00+00:00
Financial Year 2011/12
Grant Programme: Title PhD Studentship (Basic)
Has the grant transferred? No
Internal ID 099691/Z/12/Z
Lead Applicant Ms Anna M Krasnow
Planned Dates: End Date 2016-10-31T00:00:00+00:00
Planned Dates: Start Date 2012-09-24T00:00:00+00:00
Recipient Org: City London
Recipient Org: Country United Kingdom
Region London
Research conducted at multiple locations? No
Sponsor(s) Prof David Attwell
Total amount including partnership funding 198333