Translational Medicine and Therapeutics Programme at the University of Cambridge: 'Molecular imaging of glycosylation changes in Barrett's oesophagus to detect dysplasia: endoscopic and radiological applications.' (360G-Wellcome-100138_Z_12_Z)
To determine whether glycans can be used as molecular imaging targets. We hypothesise that labelled glycan can be detected endoscopically and thereby guide biopsies to macroscopically normal areas of dysplasia within Barrett’s oesophagus as prior to more generalized application in the aerodigestive tract.An in vivo endoscopic molecular imaging study using lectin-guided biopsies in the surveillance of BE will be completed as well as adapting a bioorthogonal chemistry approach from an animal model to label the human oesophageal glycome in human organ culture as a step towards to imaging of the human glycome without the application of lectins for imaging.
Where is this data from?
This data was originally published by The Wellcome Trust. If you see something about your organisation or the funding it has received on this page that doesn't look right you can submit a grantee amendment request. You can hover over codes from standard codelists to see the user-friendly name provided by 360Giving.
Grant Details
| Amount Awarded | 182345 |
| Applicant Surname | Bird-Lieberman |
| Approval Committee | PhD Studentships in Translational Medicine and Therapeutics |
| Award Date | 2012-08-31T00:00:00+00:00 |
| Financial Year | 2011/12 |
| Grant Programme: Title | Translational Medicine & Therapeutics Programme - Other Appointment |
| Internal ID | 100138/Z/12/Z |
| Lead Applicant | Dr Elizabeth Bird-Lieberman |
| Partnership Value | 182345 |
| Planned Dates: End Date | 2013-07-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2012-01-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | East of England |
| Sponsor(s) | Prof Kevin Brindle, Prof Morris Brown, Prof Rebecca Fitzgerald |