Neuronal substrates and functional importance of population dichotomy in the external globus pallidus. (360G-Wellcome-101821_Z_13_Z)

£1,755,735

Explaining the necessity and nature of functional diversity and specialization in the brain is a major endeavour of modern neuroscience. Focusing on the external globus pallidus as an exemplar neuronal system to provide a common conceptual and practical line of investigation, and scaling up from molecules to movement, this programme will systemically answer each of these fundamental questions: How is neuronal diversity molecularly specified during brain development? How do input/output or ganization and structure support a diversity of function? How do distinct cellular membrane properties and synaptic inputs interplay to orchestrate neuronal output? What is the impact of cellular diversity on network-level dynamics in space and time? Why is neuronal diversity advantageous for behaviour?

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Grant Details

Amount Awarded 1755735
Applicant Surname Magill
Approval Committee Science Interview Panel
Award Date 2013-07-10T00:00:00+00:00
Financial Year 2012/13
Grant Programme: Title Investigator Award in Science
Internal ID 101821/Z/13/Z
Lead Applicant Prof Peter Magill
Partnership Value 1755735
Planned Dates: End Date 2021-03-07T00:00:00+00:00
Planned Dates: Start Date 2014-02-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South East