Transgenerational Epigenetic Inheritance - Cichlid as the New Model (360G-Wellcome-104640_Z_14_A)

£218,440

I aim to take advantage of the cichlid fish of Malawi to study the interaction between transposable elements, non-coding RNAs, epigenetics and heritability. This is in line with the overall goal of my Investigator Award. I believe this system to be superior to equivalent experiments we might conduct in mice. This is due largely to the high phenotypic diversity and low genomic diversity of these fishes. At the time of writing of my Wellcome Trust Investigator Award the cichlid model was too immature to proceed with an experimental plan. Now we have the required genomics, RNomics and epigenetics (DNA methylation) are all in place

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Grant Details

Amount Awarded 218440
Applicant Surname Miska
Approval Committee Science Enhancement Committee
Award Date 2016-12-05T00:00:00+00:00
Financial Year 2016/17
Grant Programme: Title Enhancement
Internal ID 104640/Z/14/A
Lead Applicant Prof Eric Miska
Partnership Value 218440
Planned Dates: End Date 2019-10-09T00:00:00+00:00
Planned Dates: Start Date 2017-02-09T00:00:00+00:00
Recipient Org: Country United Kingdom
Region East of England