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Soft Robotic Total Larynx Replacement (360G-Wellcome-106574_Z_14_Z)

The technology to be developed combines novel soft robotics with proven biocompatible materials and electromyography to produce a synthetic total larynx replacement. T radWonal robotic approaches that utilise rigid material are not sufted for long term integration in the larynx due to insufficient replication of the natural musculature and physiology and the requirement for multi-component designs that increase infection risks. By exploiting advances in soft robotics, which utilises flexible and elastic intelligent materials to morph compliant structures into complex shapes, we bypass the difficultiesencountered with traditional, hard, robotics. This enables the manufacture of a monolithic synthetic larynx, made biocompatible through combination with a clinically proven airway implantable synthetic polymer. The device is controlled by electromyography of the strap muscles and muscles of the floor of the mouth, which can be preserved in laryngectomy, to infer when the patient is speaking or swallowing. The implanted device will robustly replicate the core functionality of the larynx (aspiration prevention, respiration and phonation) with a failsafe modality.

£1,395,353

27 Jan 2015

Grant details
Amount Awarded 1395353
Applicant Surname Birchall
Approval Committee Translation Fund Committee
Award Date 2015-01-27T00:00:00+00:00
Financial Year 2014/15
Grant Programme: Title Translation Fund
Internal ID 106574/Z/14/Z
Lead Applicant Prof Martin Birchall
Planned Dates: End Date 2021-02-28T00:00:00+00:00
Planned Dates: Start Date 2017-01-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Greater London
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