How are chromosomes held together by cohesin?. (360G-Wellcome-107935_Z_15_Z)

£3,174,432

1. How are chromosomes held together? 2. How does cohesin associate with chromatin and hold sisters together? 3. Mechanism of loading? 4. How is cohesion established? 5. How is dissociation regulated by acetylation? 6. Whatis the role of kinetochore cohesin during meiosis? 7. What is the structure ofcohesin and partners? 8. How does condensin hold together the DNAs of individual chromatids?

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Grant Details

Amount Awarded 3174432
Applicant Surname Nasmyth
Approval Committee Science Interview Panel
Award Date 2015-07-07T00:00:00+00:00
Financial Year 2014/15
Grant Programme: Title Investigator Award in Science
Internal ID 107935/Z/15/Z
Lead Applicant Prof Kim Nasmyth
Partnership Value 3174432
Planned Dates: End Date 2024-08-31T00:00:00+00:00
Planned Dates: Start Date 2016-09-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region South East