Anopheles-Plasmodium interactions: mosquito immune response and parasite immune evasion strategies. (360G-Wellcome-107983_Z_15_Z)
Malaria parasites entering the mosquito midgut are eliminated by robust mosquito immune reactions, and only few remain to continue the transmission cycle. My principal research questions are: how mosquito immune reactions are activated on parasites and how some parasites evade these reactions. By answering these questions, I aim to gain fundamental understanding of the Anopheles-Plasmodium interactions leading to disease transmission. This knowledge could aid future translational research for th e development of malaria transmission-blocking interventions, contributing to the global effort for malaria elimination.
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Grant Details
| Amount Awarded | 1477433 |
| Applicant Surname | Christophides |
| Approval Committee | Science Interview Panel |
| Award Date | 2015-07-07T00:00:00+00:00 |
| Financial Year | 2014/15 |
| Grant Programme: Title | Investigator Award in Science |
| Internal ID | 107983/Z/15/Z |
| Lead Applicant | Prof George Christophides |
| Partnership Value | 1477433 |
| Planned Dates: End Date | 2021-12-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2015-10-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | Greater London |