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Gene Expression Heterogeneity in the Maintenance and Coordinated Differentiation of Neuromesodermal Progenitors in vivo (360G-Wellcome-109408_Z_15_D)

<p>Modern imaging data in biology is essentially multi-scalar in that raw image data undergoes a series of processing steps until it is at a manageable size to perform quantification and analysis. While this processing pipeline might be beneficial to one set of scientific questions, it may be inappropriate to others. Computational biologists may be interested in improving the pipeline itself, while other researchers may be interested in accessing the already processed data. Thus, a central road-block in the open sharing of large-scale imaging data is the fact that there is no one size fits all solution. This project aims to generate a web-based database that stores experimental and data descriptors together with links to the&nbsp;raw and processed data files. This will greatly enhance our ability to upload this data to repositories that are based placed to share the datasets in question, from the raw unprocessed data files down to feature extracted and processed data. Upon submission, the website will link to the deposited data and thereby act as an integrated platform for other researchers to access and explore the data that is available to them. Thus, researchers will be able to access our data at all levels. In built in the project is a second evaluation phase, whereby will we reach out to collaborating laboratories to assess the effectiveness of our open research platform. These will include computational biologists interested in accessing raw data files and processing pipelines, and other developmental biologists who will interact with processed datasets.</p>

£48,563

08 Aug 2018

Grant details
Amount Awarded 48563
Applicant Surname Steventon
Approval Committee Research Enrichment, Open Research
Award Date 2018-08-08T00:00:00+00:00
Financial Year 2017/18
Grant Programme: Title Research Enrichment - Open Research
Internal ID 109408/Z/15/D
Lead Applicant Dr Benjamin Steventon
Planned Dates: End Date 2021-01-01T00:00:00+00:00
Planned Dates: Start Date 2019-01-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region East of England
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