An Analysis Of Networks And Education Resources Supporting Drug Resistant Infection Surveillance In Low And Middle Income Countries (360G-Wellcome-202961_Z_16_Z)

Supporting Surveillance Capacity for Antimicrobial Resistance: Regional Networks and Educational Resources The RFP contained three themes and this proposal is to address the terms of reference (ToR) for one of them, specifically ‘an analysis of networks and education resources supporting drug resistant infection surveillance in low and middle income countries (LMICs)’. The ToR presented two objectives (described in full in 2.1 and 2.2 below) which, in broad terms, require the identification and assessment of drug resistance surveillance ‘networks’ in LMICs and of available ‘educational resources’ designed to support effective implementation of such networks. We would define a drug resistance surveillance network as a group of institutions (nationally) or countries (regionally/globally) that gather, analyse, compile and share the results of any aspect of antimicrobial resistance (e.g. antimicrobial resistance, antimicrobial use and antimicrobial quality). The Capacity Research Unit (CRU), Liverpool School of Tropical Medicine (LSTM), has extensive experience assessing laboratory and research systems within LMICs and identifying site-­- and system-­- specific capacity strengthening pathways(1, 2). As such, we believe we are strongly positioned to meet the stated ToR objectives which we would achieve by drawing on our existing expertise and networks to complete the following five activities: 1) Identify drug resistance surveillance networks through a systematic review of the published and grey literature and through consultation with existing contacts in LMICs and relevant research and development organisations. 2) Assess the scope, strengths and weaknesses of each identified network against a study-­-specific evaluation matrix. The matrix will be informed by existing surveillance system benchmarks such as the WHOs Global Antimicrobial Resistance Surveillance System (GLASS) (3) and the OASIS tool for assessing epidemiological surveillance systems (4). The assessment of each surveillance network will be based on information obtained during the aforementioned review of published and grey literature and through key informant interviews with members from each network or individuals with working knowledge of a network. 3) Produce a report comparing and contrasting each network according to the evaluation matrix, identifying best performing networks regionally and detailing key recommendations for strengthening regional surveillance networks. 4) Identify existing educational resources to support strengthening of current drug resistant infection surveillance systems through a systematic review of the published and grey literature, through consultation with existing contacts in LMICS and relevant research and development organisations and during the aforementioned key informant interviews with network members. 5) Produce a report detailing the identified education resources, their respective scope (i.e. which component(s) of a surveillance system they are designed to support) and how to access them. The report will also detail current gaps in the available education resources, with respect to both scope and access. In completing the above, we envisage some cross over with another Fleming Fund RFP "An analysis of approaches to laboratory capacity strengthening for drug resistant infections in LMICs" for which CRU have also submitted a proposal.

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Grant Details

Amount Awarded 4981
Applicant Surname Bates
Approval Committee Internal Decision Panel for C&S
Award Date 2016-09-30T00:00:00+00:00
Financial Year 2015/16
Grant Programme: Title Discretionary award – DRI
Internal ID 202961/Z/16/Z
Lead Applicant Prof Imelda Bates
Partnership Name The Fleming Fund
Partnership Value 18184
Planned Dates: End Date 2016-06-29T00:00:00+00:00
Planned Dates: Start Date 2016-03-29T00:00:00+00:00
Recipient Org: Country United Kingdom
Region North West