(Pilot) InterTxt2Heart pilot: A trial to evaluate efficacy of text message to improve adherence to cardiovascular medications in secondary prevention. (360G-Wellcome-202975_Z_16_Z)
We plan to conduct a large international randomized controlled study that will evaluate the efficacy and safety of mobilephones short messages services (SMS) on adherence to cardiovascular disease (CVD) secondary prevention medications.For this funding call we are applying for the development phase of this study.Our specific objectives for this development study are :(1) Develop an appropriate content of mobile phone SMS addressing context-dependent causes of poor adherence and;(2) Develop the most appropriate trial design needed to evaluate the efficacy and safety of SMS to increase adherence tocardiovascular secondary prevention medications.The main research questions that we will address in this development grant are:1) What are the causes for poor adherence to CVD medications used for secondary prevention in each of the includedcountries?2) Which of these causes are likely to be modifiable by SMS delivery of effective behaviour change techniques (BCTs)?3) How can selected BCTs be operationalised as effective and simple SMS messages adapted to local context?4) How will the patterns of clinical care within each country impact on required sample size?5) What is the feasibility (and acceptability) of patient recruitment within selected centres?6) How suitable are the pre-selected e-platform (CommCare, Dimagi) and instruments for steps involved in the trial?
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Grant Details
Amount Awarded | 30270 |
Applicant Surname | Perel |
Approval Committee | Joint Global Health Trials Committee |
Award Date | 2015-11-16T00:00:00+00:00 |
Financial Year | 2015/16 |
Grant Programme: Title | Joint Global Health Trials Award |
Internal ID | 202975/Z/16/Z |
Lead Applicant | Prof Pablo Perel |
Partnership Name | Joint global health trials |
Partnership Value | 30270 |
Planned Dates: End Date | 2017-03-30T00:00:00+00:00 |
Planned Dates: Start Date | 2016-04-01T00:00:00+00:00 |
Recipient Org: Country | United Kingdom |
Region | Greater London |