Wellcome Centre for Human Neuroimaging (360G-Wellcome-203147_Z_16_Z)

Our vision is to deliver clinically-transformative applications of neuroimaging that provide computationally-derived biomarkers for personalised prognosis and treatment planning. We investigate how the human brain functions in health and disease and how this knowledge can inform prognoses in patients with neurological and psychiatric disorders. By integrating cutting-edge neuroimaging technologies with neuronal and behavioural modelling, we seek to establish non-invasive quantitative measures of neuronal function that can be used to identify pathophysiology, deliver personalised prognoses, and develop or assess therapeutic interventions. Our strategy combines two key elements that are unique to our location, staff and facilities. First, we bring together internationally-renowned expertise in neuroimaging, biophysical modelling, cognitive, computational, mathematical and clinical neuroscience. Second, we create an environment that fosters interactions between those asking key neurobiological questions and those developing methods and theories that make these questions tractable. Our clinical focus reflects a long-standing commitment to developing neuroimaging methods that provide mechanistic explanations of how the human brain supports sensory, motor and cognitive functions in health, how these mechanisms are affected by disease, and how they respond to therapeutic interventions. We are in a unique position to conduct this work given our our location opposite the National Hospital for Neurology and Neurosurgery.