UK Biobank (360G-Wellcome-205339_Z_16_Z)

As summarised in the extracted text below from our full application (page 5 "Proposed work") in Section 10 of this application form (and described in more detail on pages 5-16 of Section 10). During the next 5 years, it is intended to: \- Extend cohort-wide linkage to primary care health records, while maintaining and updating health outcome data from existing linkages to death, cancer and hospital records (and explore the added value of linkages to additional healthcare datasets); \- Further develop and implement large-scale identification and characterization of many different types of health outcome; \- Streamline the research access systems, and improve methods for processing, presenting and providing linked healthcare data to researchers; \- Maintain the sample resource, and make increasing amounts of different types of genotype and biomarker data available; \- Conduct imaging assessments in 100,000 participants, and develop and implement further enhancements (such as cardiac monitoring and further sample collection and assays). Efforts will continue to be made to ensure that researchers from around the world are suitably well informed about the resource so that the effective use of it increases substantially, leading to novel findings that have a major impact on human health.