The Science of Rabies Elimination (360G-Wellcome-207569_Z_17_Z)

£2,290,232

Rabies is a horrific, but vaccine-preventable disease that kills thousands of people every year in low-income countries. International agencies now advocate investment in rabies control and have set a 2030 target for global elimination. With regional programmes underway, the major research questions are now how to optimize rollout and impact, addressing challenges as elimination is approached. My fellowship aims to address these questions through synergistic research embedded within large-scale rabies control programmes around the world.   Through a large-scale vaccination intervention in Tanzania I will test the hypothesis that rabies circulates at low incidence with spatial correlations in transmission curtailing outbreaks through localized susceptible depletion, and permitting co-circulation of genetically divergent lineages. I will pilot surveillance approaches to increase case detection, improve patient care, track the spread of infection and inform elimination programmes. The resulting data will be used to formulate and parametrize models to investigate strategies to rapidly control rabies, minimize incursion risks, and maintain disease freedom.   A global network of scientists, policy-makers, and practitioners provides an enabling environment for my intervention-based research across intercontinental settings. Findings will therefore translate directly into policy at the highest level, delivering impact through timely transferrable insights to guide elimination efforts.

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Grant Details

Amount Awarded 2290232
Applicant Surname Hampson
Approval Committee Science Interview Panel
Award Date 2017-07-11T00:00:00+00:00
Financial Year 2016/17
Grant Programme: Title Senior Research Fellowship Basic
Internal ID 207569/Z/17/Z
Lead Applicant Prof Katie Hampson
Partnership Value 2290232
Planned Dates: End Date 2022-10-31T00:00:00+00:00
Planned Dates: Start Date 2017-10-01T00:00:00+00:00
Recipient Org: Country United Kingdom
Region Scotland
Sponsor(s) Prof Daniel Haydon