Assessing human immune organ architecture in a humanised mouse model following schistosome egg injection (360G-Wellcome-211686_Z_18_Z)
This research will assess human immune organ architecture in humanised mice following injection with schistosome eggs. We will generate tissue samples from the spleen, lymph node and bone marrow from naive and schistosome-immunised mice to compare and contrast the localisation of CD4 T cells, B cells, macrophages, dendritic cells and eosinophils. We do not know much about whether these cells interact together in a way that produces a string type 2 immune response, this project aims to test this in an acute model of immunity.
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Grant Details
| Amount Awarded |
0
|
| Applicant Surname | Connolly |
| Approval Committee | Internal Decision Panel |
| Award Date | 2018-05-31T00:00:00+00:00 |
| Financial Year | 2017/18 |
| Grant Programme: Title | Vacation Scholarships |
| Internal ID | 211686/Z/18/Z |
| Lead Applicant | Miss Ciara Connolly |
| Partnership Value | 0 |
| Planned Dates: End Date | 2018-08-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2018-07-01T00:00:00+00:00 |
| Recipient Org: Country | United Kingdom |
| Region | Yorkshire and the Humber |