The Avon Longitudinal Study of Parents and Children (ALSPAC): A multi- generation, longitudinal resource focusing on life course health and well- being. (360G-Wellcome-217065_Z_19_Z)

£4,163,648

ALSPAC is a multi-generation (G0/G1/G2), prospective cohort based in the UK [1-4] (supplementary information, Figure 1). This proposal seeks support to: - Maintain the existing samples and data resources. - Enhance visibility and access to data and samples. - Maximise linkage opportunities through broad and innovative use of administrative records. - Expand the resource by maximising recruitment and retention, and collecting new data and samples on original parents (G0), index participants (G1) and the next generation (G2). Work will be delivered via an efficient operational and governance infrastructure. We will deploy a combination of face-to-face assessment, biosample collection and analysis, remote data collection and administrative record linkage where the value of this activity is substantially enhanced by existing resources. All proposed work has been designed according to the overarching principles of (i) scientific utility and (ii) engagement/recruitment/retention. Study activities draw on experience from previous ALSPAC activity and consultation with participants and academics through bespoke workshops. Scientific focus reflects ALSPAC strengths and our target science areas, namely: The antecedents of cardiometabolic/cognitive/mental health, cross-generation contributions to health and era specific contributions to health, well-being and society.

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Grant Details

Amount Awarded 4163647.5
Applicant Surname Timpson
Approval Committee Longitudinal Population Studies Committee
Award Date 2019-05-22T00:00:00+00:00
Financial Year 2018/19
Grant Programme: Title Longitudinal Population Studies
Has the grant transferred? No
Internal ID 217065/Z/19/Z
Lead Applicant Prof Nicholas John Timpson
Other Applicant(s) Prof Abigail Fraser, Prof Kate Tilling, Prof George Davey Smith, Prof Yoav Ben-Shlomo, Prof Matthew Hickman, Prof John Macleod, Dr Russell Jago, Dr Susan M Ring, Ms Lynn Catherine Molloy, Prof Deborah A Lawlor, Dr Kate Northstone
Partnership Name Avon Longitudinal Study of Parents and Children (ALSPAC)
Planned Dates: End Date 2024-07-31T00:00:00+00:00
Planned Dates: Start Date 2019-08-01T00:00:00+00:00
Recipient Org: City Bristol
Recipient Org: Country United Kingdom
Region South West
Research conducted at multiple locations? No
Total amount including partnership funding 8327295