The Avon Longitudinal Study of Parents and Children (ALSPAC): A multi- generation, longitudinal resource focusing on life course health and well- being. (360G-Wellcome-217065_Z_19_Z)
ALSPAC is a multi-generation (G0/G1/G2), prospective cohort based in the UK [1-4] (supplementary information, Figure 1). This proposal seeks support to: - Maintain the existing samples and data resources. - Enhance visibility and access to data and samples. - Maximise linkage opportunities through broad and innovative use of administrative records. - Expand the resource by maximising recruitment and retention, and collecting new data and samples on original parents (G0), index participants (G1) and the next generation (G2). Work will be delivered via an efficient operational and governance infrastructure. We will deploy a combination of face-to-face assessment, biosample collection and analysis, remote data collection and administrative record linkage where the value of this activity is substantially enhanced by existing resources. All proposed work has been designed according to the overarching principles of (i) scientific utility and (ii) engagement/recruitment/retention. Study activities draw on experience from previous ALSPAC activity and consultation with participants and academics through bespoke workshops. Scientific focus reflects ALSPAC strengths and our target science areas, namely: The antecedents of cardiometabolic/cognitive/mental health, cross-generation contributions to health and era specific contributions to health, well-being and society.
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Grant Details
Amount Awarded | 4163647.5 |
Applicant Surname | Timpson |
Approval Committee | Longitudinal Population Studies Committee |
Award Date | 2019-05-22T00:00:00+00:00 |
Financial Year | 2018/19 |
Grant Programme: Title | Longitudinal Population Studies |
Has the grant transferred? | No |
Internal ID | 217065/Z/19/Z |
Lead Applicant | Prof Nicholas John Timpson |
Other Applicant(s) | Prof Abigail Fraser, Prof Kate Tilling, Prof George Davey Smith, Prof Yoav Ben-Shlomo, Prof Matthew Hickman, Prof John Macleod, Dr Russell Jago, Dr Susan M Ring, Ms Lynn Catherine Molloy, Prof Deborah A Lawlor, Dr Kate Northstone |
Partnership Name | Avon Longitudinal Study of Parents and Children (ALSPAC) |
Planned Dates: End Date | 2024-07-31T00:00:00+00:00 |
Planned Dates: Start Date | 2019-08-01T00:00:00+00:00 |
Recipient Org: City | Bristol |
Recipient Org: Country | United Kingdom |
Region | South West |
Research conducted at multiple locations? | No |
Total amount including partnership funding | 8327295 |