The Avon Longitudinal Study of Parents and Children (ALSPAC): A multi- generation, longitudinal resource focusing on life course health and well- being. (360G-Wellcome-217065_Z_19_Z)
ALSPAC is a multi-generation (G0/G1/G2), prospective cohort based in the UK [1-4] (supplementary information, Figure 1). This proposal seeks support to: \- Maintain the existing samples and data resources. \- Enhance visibility and access to data and samples. \- Maximise linkage opportunities through broad and innovative use of administrative records. \- Expand the resource by maximising recruitment and retention, and collecting new data and samples on original parents (G0), index participants (G1) and the next generation (G2). Work will be delivered via an efficient operational and governance infrastructure. We will deploy a combination of face-to-face assessment, biosample collection and analysis, remote data collection and administrative record linkage where the value of this activity is substantially enhanced by existing resources. All proposed work has been designed according to the overarching principles of (i) scientific utility and (ii) engagement/recruitment/retention. Study activities draw on experience from previous ALSPAC activity and consultation with participants and academics through bespoke workshops. Scientific focus reflects ALSPAC strengths and our target science areas, namely: The antecedents of cardiometabolic/cognitive/mental health, cross-generation contributions to health and era specific contributions to health, well-being and society.
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Grant Details
| Region | South West |
| Award Date | 2019-05-22T00:00:00+00:00 |
| Internal ID | 217065/Z/19/Z |
| Planned Dates: End Date | 2024-07-31T00:00:00+00:00 |
| Planned Dates: Start Date | 2019-08-01T00:00:00+00:00 |
| Amount Awarded | 4163647.5 |
| Financial Year | 2018/19 |
| Lead Applicant | Prof Nicholas John Timpson |
| Grant Programme: Title | Longitudinal Population Studies |
| Partnership Name | Avon Longitudinal Study of Parents and Children (ALSPAC) |
| Applicant Surname | Timpson |
| Approval Committee | Longitudinal Population Studies Committee |
| Other Applicant(s) | Prof George Davey Smith, Prof Kate Tilling, Prof Matthew Hickman, Prof Yoav Ben-Shlomo, Prof Abigail Fraser, Dr Susan M Ring, Dr Kate Northstone, Ms Lynn Catherine Molloy, Prof John Macleod, Prof Deborah A Lawlor, Dr Russell Jago |
| Recipient Org: Country | United Kingdom |
| Recipient Org: City | Bristol |
| Has the grant transferred? | No |
| Research conducted at multiple locations? | No |
| Total amount including partnership funding | 8327295 |