The ISARIC data platform: Optimizing data-driven pandemic preparedness and response (360G-Wellcome-225288_Z_22_Z)

Taking the lessons learned from the international success of ISARIC’s COVID-19 data platform, we will expand the platform to answer new questions on COVID-19 and build data systems to respond to future outbreaks of infectious diseases. This collaboration brings together scientists who have developed world-leading data integration, processing and analytic technologies with health care workers and public health specialists who will use and tailor the technologies to deliver evidence that's relevant to patient care and public health policy decisions. Together we will expand the data platform to 1) integrate epidemiological and clinical data so that we can analyse research questions at an individual level and a population level; 2) integrate genomic data so that we can understand how different virus variants affect patient outcomes; and 3) provide the infrastructure to scale data processing and grow our international network to generate more evidence on emerging infectious diseases. We will analyse these integrated data sets to generate evidence on the impact of vaccination and new variants in COVID-19 infection and post-acute COVID-19 syndrome. We will also develop methods to accelerate science on the characterisation of future disease outbreaks.