Understanding asthma through population-scale long-read sequencing of diverse genomes (360G-Wellcome-337623_Z_25_Z)
Understanding the diversity of human genomes is important for understanding the contribution of genetic variation to disease, including asthma. Despite much progress in understanding, we have very limited understanding in two areas - genomes from those of non-European ancestry, and complex genetic structural variation, such as variation in gene copy number variation. Using long read genome sequencing, two large projects (1000 Genomes Project and Genomics England) are beginning to address this. The project will focus on the role of structural variants in respiratory disease, in particular asthma, but there will be opportunities to answer more fundamental biological questions on the population genetics of structural variants as well.
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Grant Details
| Region | East Midlands |
| Award Date | 2025-12-31T00:00:00+00:00 |
| Sponsor(s) | Prof Edward Hollox |
| Internal ID | 337623/Z/25/Z |
| Planned Dates: End Date | 2028-09-30T00:00:00+00:00 |
| Planned Dates: Start Date | 2025-10-01T00:00:00+00:00 |
| Amount Awarded |
0
|
| Financial Year | 2025/26 |
| Lead Applicant | Miss Lucy Stella Webster |
| Grant Programme: Title | PhD Studentship (Basic) |
| Applicant Surname | Webster |
| Approval Committee | Discretionary Award decision meeting |
| Recipient Org: Country | United Kingdom |
| Recipient Org: City | Leicester |
| Has the grant transferred? | No |
| Research conducted at multiple locations? | No |
| Total amount including partnership funding | 0 |