The forgotten groups in global Hepatitis B strategy (360G-Wellcome-344447_Z_26_Z)
Hepatitis B virus (HBV) affects 254 million people worldwide, and 4.5 million women living with surface antigen-positive (HBsAg-positive) HBV infection give birth annually. Approximately 90% of infants born to these mothers do not become infected. These HBsAg-exposed uninfected(HBEU) infants are typically excluded from HBV research and policy, but preliminary data from a Zimbabwean cohort suggests HBEU infants have increased morbidity compared to unexposed children. Women with Occult HBV infection(OBI) are also neglected in global health policies. In OBI, conventional assays fail to detect HBsAg, but DNA is positive. Data suggest a 6-12% OBI prevalence in high HBV-endemic countries, but the prevalence and impact of OBI in most settings is unknown. Together, OBI and HBsAg-positive infection means HBV-infection may be as common as HIV but is much more overlooked. Sub-Saharan Africa is estimated to have the highest global OBI prevalence rate but constitutes
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Grant Details
| Region | London |
| Award Date | 2026-06-12T00:00:00+00:00 |
| Sponsor(s) | Prof Andrew Prendergast |
| Internal ID | 344447/Z/26/Z |
| Planned Dates: End Date | 2028-09-04T00:00:00+00:00 |
| Planned Dates: Start Date | 2025-09-05T00:00:00+00:00 |
| Amount Awarded |
0
|
| Financial Year | 2025/26 |
| Lead Applicant | Dr Elaine Parker |
| Grant Programme: Title | PhD Studentship for Health Professionals |
| Applicant Surname | Parker |
| Approval Committee | Discretionary Award decision meeting |
| Recipient Org: Country | United Kingdom |
| Recipient Org: City | London |
| Has the grant transferred? | No |
| Research conducted at multiple locations? | No |
| Total amount including partnership funding | 0 |